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2.A.3.3.11
Cationic amino acid transporter 8, vacuolar

Accession Number:Q9SHH0
Protein Name:Cationic amino acid transporter 8, vacuolar
Length:590
Molecular Weight:64862.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

Genevestigator: Q9SHH0
eggNOG: COG0531
HEGENOM: HOG000237636
Entrez Gene ID: 838282   
KEGG: ath:AT1G17120   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005774 C:vacuolar membrane
GO:0015171 F:amino acid transmembrane transporter activity

References (4)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “Molecular and functional characterization of a family of amino acid transporters from Arabidopsis.”  Su Y.-H.et.al.   15377779
[4] “A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture.”  Jaquinod M.et.al.   17151019

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIPASMEEAH QLESRSDDLS QRRSYWRWRK QDFFPEFSFQ SFSTYKSALS ATCPRLADRL 
61:	LSRSSDAYEL DAARRESENP MRRCLTWWDL LWLSFGSVVG SGVFVITGQE ARVGAGPAVV 
121:	LSYAISGVSA LLSVLCYAEF GVEIPVAGGS FSYLRVELGD FIAFIAAGNI LLEAMVGAAG 
181:	LGRSWSSYLA SLVKNDSDYF RIKVDSFAKG FDLLDPVAVA VLLVANGIAM TGTKRTSWLN 
241:	LITSMVTVCI IVFIVVVGFT HSKTSNLVPF FPYGAKGVVQ SAAVVYWSYT GFDMVANMAE 
301:	ETEKPSRDIP IGLVGSMSMI TVVYCLMALA LTMMVKYTEI DANAAYSVAF AQIGMKWAKY 
361:	LVGICALKGM TTSLLVGSLG QARYTTQIAR SHMIPPWFAL VHPKTGTPIY ATLLVTILSS 
421:	IISFFTSLEV LSSVFSFATL FIFMLVAVAL LVRRYYVKDV TPEAGLLKFL GFLFLIIASS 
481:	IGVSALWNSG VKGWIAYTVT GVIWFIGTLG LALLPKYRVP KVWGVPLVPW LPSFSIAMNL 
541:	FLIGSLGYVA FLRFIICTMV MLLYYLFVGL HATYDVAHQP LEEAKFEGER