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2.A.3.3.14
Cationic amino acid transporter 4, vacuolar

Accession Number:Q8W4K3
Protein Name:Cationic amino acid transporter 4, vacuolar
Length:600
Molecular Weight:63639.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

Genevestigator: Q8W4K3
HEGENOM: HOG000250623
Entrez Gene ID: 821176   
KEGG: ath:AT3G03720   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005774 C:vacuolar membrane
GO:0015171 F:amino acid transmembrane transporter activity

References (4)

[1] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “Molecular and functional characterization of a family of amino acid transporters from Arabidopsis.”  Su Y.-H.et.al.   15377779
[4] “A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture.”  Jaquinod M.et.al.   17151019

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNSLVRRKQV DSVHLIKNDG PHQLAKKLSA VDLVAIGVGT TIGAGVYILV GTVAREHTGP 
61:	ALAVSFFIAG VAAALSACCY AELASRCPSA GSAYHYAYIC LGEGIAWLVG WALVLDYTIG 
121:	GSAIARGITP NLASFFGGLD NLPVFLARQT IPGVGIVVDP CAALLIMIVT ILLCFGIKES 
181:	STVQAIVTSV NVCTLVFIIV VGGYLACKTG WVGYDLPSGY FPFGLNGILA GSAVVFFSYI 
241:	GFDTVTSTAE EVKNPQRDLP LGIGIALLIC CILYMLLSVV IVGLVPYYSL NPDTPISSAF 
301:	GDSGMQWAAY ILTTGAITAL CASLLGSLLA QPRIFMAMAR DGLLPAFFSE ISPRTQVPVK 
361:	STIAIGVLAA ALAFFMDVAQ LSEMVSVGTL MAFTAVAVCV LVLRYVPPDG VPLSSSSQTL 
421:	SDTDESRAET ENFLVDAIES SDSPLLGNET ARDEKYFGKR RKIAAWSIAL VCIGVLGLAS 
481:	AASAERLPSF PRFTICGVSA VILLGSLITL GYIDEDEERH NFGHKGGFLC PFVPYLPVLC 
541:	ILINTYLIIN IGAGTWIRVL IWLLIGSMIY IFYGRSHSLL NNAVYVPTMT CTRKTTDHLA