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2.A.3.3.19
Histamine uptake transporter; involved in the utilization of histamine as a nitrogen source.  In an operon with two histamine catabilic enzymes, and all are induced by hsitamine (Johnson et al. 2008).

Accession Number:Q9I6R8
Protein Name:Amino acid APC family transporter
Length:477
Molecular Weight:50595.00
Species:Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) [208964]
Number of TMSs:12
Substrate Histamine

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNDTPNVREP ALRRVLGLGP LLAVAIGLVV SQGVMVLMLQ GAGTAGLGFI VPLGVAYLLA 
61:	LSYAFSFSEL ALMIPRAGSL SSYTEVAIGH FPAILATFSG YVVVAMFALS AELLLLDLII 
121:	GKVYPGALPP MLVAYGVLGL FTLLNLLGID IFARLQSALA LLMMIVLLVL GLGAVSSDHA 
181:	SAQTALASGW NPLGVSALAL TAMAVWGFVG AEFVCPLVEE TRRPERNIPR SMILGLSIIF 
241:	LTIALYCFGA LLCIPQAELA GDPLPHFLFA NRVFGEYGQL FLVIAAITAT CSTLNSSLAA 
301:	IPRMLYGMAQ NGQAFPQFKQ LSRRARTPWV AVLFVAAITG LPILILGQDP DSINLLLLAA 
361:	ALAWLLAYII AHVDVLALRR RYPHIARPFR TPFYPLPQLF GIAGMIYAVV HVSPTPEMTG 
421:	RIFASAGVVL GVVSLVAVVW IKGVMRKPLF VPEPLETAGE TAQGKSVALD PLQSPSA