TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.3.3.4
The amino acid transporter, CAT6. Mediates electrogenic transport of large neutral and cationic amino acids in preference to other amino acids. Present in lateral root primordia, flowers and seeds (Hammes et al., 2006)

Accession Number:Q9LZ20
Protein Name:Cationic amino acid transporter 6 aka CAT6
Length:583
Molecular Weight:62809.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

Genevestigator: Q9LZ20
eggNOG: KOG1286
HEGENOM: HBG588653
RefSeq: NP_196097.1   
Entrez Gene ID: 830355   
Pfam: PF00324   
KEGG: ath:AT5G04770   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0009624 P:response to nematode
GO:0055085 P:transmembrane transport

References (3)

[1] “Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.”  Tabata S.et.al.   11130714
[2] “Full-length messenger RNA sequences greatly improve genome annotation.”  Haas B.J.et.al.   12093376
[3] “Structural analysis of Arabidopsis thaliana chromosome 5. III. Sequence features of the regions of 1,191,918 bp covered by seventeen physically assigned P1 clones.”  Nakamura Y.et.al.   9501997

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MEVQSSSNNG GHSSFSSLRV YLNSLSATPS RLSRRAISVS TSSDEMSRVR AVSGEQMRRT 
61:	LRWYDLIGLG IGGMVGAGVF VTTGRASRLD AGPSIVVSYA IAGLCALLSA FCYTEFAVHL 
121:	PVAGGAFSYI RITFGEFPAF FTGANLVMDY VMSNAAVSRS FTAYLGTAFG ISTSKWRFVV 
181:	SGLPKGFNEI DPVAVLVVLV ITVIICCSTR ESSKVNMIMT AFHIAFIFFV IVMGFIKGDS 
241:	KNLSSPANPE HPSGFFPFGA AGVFNGAAMV YLSYIGYDAV STMAEEVENP VKDIPVGVSG 
301:	SVAIVTVLYC LMAVSMSMLL PYDLIDPEAP FSAAFRGSNG WEWVTKVVGI GASFGILTSL 
361:	LVAMLGQARY MCVIGRSRVV PFWFAKIHPK TSTPVNASTF LGIFTAALAL FTDLNVLLNL 
421:	VSIGTLFVFY MVANALIFRR YVPVGPTKPW PTLCFLTLFS ITSLVFTLIW KLVPEGKPKA 
481:	FMLGASAVVA IAIVLSFQCV VPQARKPELW GVPFMPWTPC VSIFLNIFLL GSLDAPSYVR 
541:	FGFFSGLIVL VYLFYGVHAS SDAEANGSFG VKDGQVMKEL IEV