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2.A.3.5.2
Probable methylamine import permease

Accession Number:Q8TUC6
Protein Name:MTTP or MA0143
Length:468
Molecular Weight:51100.00
Species:Methanosarcina acetivorans [2214]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Methylamine

Cross database links:

HEGENOM: HBG540217
RefSeq: NP_615116.1   
Entrez Gene ID: 1472035   
Pfam: PF00324   
BioCyc: MACE188937:MA0143-MONOMER   
KEGG: mac:MA0143   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (1)

[1] “The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity.”  Galagan J.E.et.al.   11932238

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSEHYESASL VKTLRPFHVW ALGVGIVLVG EYMGWNFTVA KGGVLGSLLA MLVAGTMYVI 
61:	ISLCASELGA ATKLAGGPYD WARLFIGPGA AASVGLAVYM EYIALEAADA IVVAFIAQSI 
121:	FPELQVFPVT LLVIALLTFI NYRGVVAALT LNFFLTMIAF ISIVVFFFAT AFGGVDIHPE 
181:	YLFHGALPNG MIGLFAALQF GPWFYLGIEG AAMCAEECKH PSRAVPLGQQ AGMITLLVGA 
241:	AMTLYLCSVL IPTDQLGVSV YPLFEAAQNS GMFIFIALLG LGTFLTCVAS ANGCVCDSSR 
301:	SWFALSRDNY VSSWFSAVHP RYNTPYRAVI FTMPVAIGFA FSGFLDQVIT FSIVSGLLCY 
361:	VLIPFALIRF RSLFPQNTST IRPFVSPLQP YIAYFAIAIA ITILSTLYWG YKYNLIFAFV 
421:	FYGIAYFYFS HRHRSLNIEN NWTEMGWPLP RGSENTGIRK EATGIGDE