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2.A.3.6.2
The putative permease, MtbP (MA2426) (possibly a methyl amine uptake porter; D.J. Ferguson, personal communication) (12 putative TMSs)

Accession Number:Q8TN67
Protein Name:Amino acid permease
Length:505
Molecular Weight:54702.00
Species:Methanosarcina acetivorans [2214]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Secreted1
Substrate Methylamine

Cross database links:

HEGENOM: HBG122316
RefSeq: NP_617332.1   
Entrez Gene ID: 1474315   
Pfam: PF00324   
BioCyc: MACE188937:MA2426-MONOMER   
KEGG: mac:MA2426   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (1)

[1] “The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity.”  Galagan J.E.et.al.   11932238

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MVISMDDNTH SSQIDWQYAE ECSRASCDLK ELERSIDWKQ GLAIALGVPL LILPSIGYFT 
61:	GYVWAFSIII WALTIFLGFF QNLAFGELAT VFPKASGLPG YTQTVFGSSS NSNNKGKFKF 
121:	GKFIGGFSAW SYWFGWSPVL AIYAILIGSY LKGLVPAFSG VPDTLLSLMV GALIFGSLAI 
181:	INSKGLKNGA MAGYILAVVS LIPLIVITVA PFLTGDFHLA NITSSWFPTD WTWDMKHILI 
241:	LFGIFAMAEW SACAWETAAI YGPEYKNPNT DTPKALLVCG GICLVLYVLV QTSVIGTLGV 
301:	EGVLSEPISP MLPIANLTLG ALGASIAIIM LVGAMLLIIQ TAFLSSARSI YSMSTEGNLP 
361:	AVLSKLNSHG HPMNAMIADA LFNMGLILLG TPTAILAASA IGYIFANGIS LYTYVKVRND 
421:	PKLSKLDRPF KAPNGWKNVA MATAILNIPF FLVGIIYLNS LELGWATTGV GFFVLCLYVP 
481:	LWFYSQRETR KTEEKMAAEK EAVIV