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2.A.3.6.3
ApcT, a proton coupled broad specificity amino acid transporter.  3-d structure available at 2.3Å resolution (3GIA_A; Shaffer et al., 2009).

Accession Number:Q58026
Protein Name:Uncharacterized protein MJ0609
Length:435
Molecular Weight:47358.00
Species:Methanocaldococcus jannaschii [2190]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Amino acids

Cross database links:

HEGENOM: HBG575406
RefSeq: NP_247591.1   
Entrez Gene ID: 1451474   
Pfam: PF00324   
KEGG: mja:MJ0609   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.”  Bult C.J.et.al.   8688087
Structure:
3GI8   3GI9   3GIA     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MELKNKKLSL WEAVSMAVGV MIGASIFSIF GVGAKIAGRN LPETFILSGI YALLVAYSYT 
61:	KLGAKIVSNA GPIAFIHKAI GDNIITGALS ILLWMSYVIS IALFAKGFAG YFLPLINAPI 
121:	NTFNIAITEI GIVAFFTALN FFGSKAVGRA EFFIVLVKLL ILGLFIFAGL ITIHPSYVIP 
181:	DLAPSAVSGM IFASAIFFLS YMGFGVITNA SEHIENPKKN VPRAIFISIL IVMFVYVGVA 
241:	ISAIGNLPID ELIKASENAL AVAAKPFLGN LGFLLISIGA LFSISSAMNA TIYGGANVAY 
301:	SLAKDGELPE FFERKVWFKS TEGLYITSAL GVLFALLFNM EGVASITSAV FMVIYLFVIL 
361:	SHYILIDEVG GRKEIVIFSF IVVLGVFLLL LYYQWITNRF VFYGIIATFI GVLIFEIIYR 
421:	KVTKRTFSNN MYVKS