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2.A.3.7.5
Inner membrane transporter, YjeM of 500 aas and 12 TMSs. Probably an amino acid transporter, possibly an amino acid:organic amine antiporter.

Accession Number:P39282
Protein Name:Inner membrane transporter yjeM
Length:500
Molecular Weight:54725.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P39282
EchoBASE: EB2368
EcoGene: EG12475
eggNOG: COG0531
HEGENOM: HOG000127295
Entrez Gene ID: 948679   
KEGG: eco:b4156   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015171 F:amino acid transmembrane transporter activity

References (4)

[1] “Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.”  Burland V.D.et.al.   7610040
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPHTIKKMSL IGLILMIFTS VFGFANSPSA YYLMGYSAIP FYIFSALLFF IPFALMMAEM 
61:	GAAYRKEEGG IYSWMNNSVG PRFAFIGTFM WFSSYIIWMV STSAKVWVPF STFLYGSDMT 
121:	QHWRIAGLEP TQVVGLLAVA WMILVTVVAS KGINKIARIT AVGGIAVMCL NLVLLLVSIT 
181:	ILLLNGGHFA QDINFLASPN PGYQSGLAML SFVVFAIFAY GGIEAVGGLV DKTENPEKNF 
241:	AKGIVFAAIV ISIGYSLAIF LWGVSTNWQQ VLSNGSVNLG NITYVLMKSL GMTLGNALHL 
301:	SPEASLSLGV WFARITGLSM FLAYTGAFFT LCYSPLKAII QGTPKALWPE PMTRLNAMGM 
361:	PSIAMWMQCG LVTVFILLVS FGGGTASAFF NKLTLMANVS MTLPYLFLAL AFPFFKARQD 
421:	LDRPFVIFKT HLSAMIATVV VVLVVTFANV FTIIQPVVEA GDWDSTLWMI GGPVFFSLLA 
481:	MAIYQNYCSR VAKNPQWAVE