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2.A.3.8.16
Low-affinity methionine permease, MUP3

Accession Number:P38734
Protein Name:Low-affinity methionine permease
Length:546
Molecular Weight:60620.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Methionine

Cross database links:

Genevestigator: P38734
eggNOG: COG0531
HEGENOM: HOG000187297
DIP: DIP-5572N
Entrez Gene ID: 856349   
KEGG: sce:YHL036W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015191 F:L-methionine transmembrane transporter activity

References (3)

[1] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.”  Johnston M.et.al.   8091229
[2] “The study of methionine uptake in Saccharomyces cerevisiae reveals a new family of amino acid permeases.”  Isnard A.D.et.al.   8893857
[3] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MEPLLFNSGK ANPSQDVFID VEVGDITTKY GSTNTGSFSS MDTVEAQAIK AETARFMEVP 
61:	QGRHLGVFST VVLFVSRIMG SGIFAVPSVI LLNTGGNKLI YFAIWVFSAA IAFAGLYLFL 
121:	EFGSWIPKSG GRKNFLERSF ERPRLLISVV FSCYSVLTGY ALTGSIVFGK YVLSAFGVTD 
181:	DSWSKYVSIS FIIFAVLIHG VSVRHGVFIQ NALGGLKLIM IVLMCFAGLY TLFFYKSTGQ 
241:	VAWDLPVTQV EKDSLLSVSS IATAFISSFF CFSGWDTVHT VTSEIKNPVK TLKVSGPLSL 
301:	IICFVCYTMM NVAYLKVLTY EEIVSAGPLV GSVLFTKLFG PRVGGKFIAF SIAISAASNI 
361:	LVVIYSISRV NQEIFKEGYL PFSIHMSKNW PFDAPLPSIS LCGFITIAWI LILPKEGESF 
421:	NYLVSMDGYG NQFFLLLVAI GLFIWRFKHK NEVPEIRAST FGVLAIITLS LYMLMAPFFA 
481:	DPSLNRVGFL PPYQIMSLLV IVACFFFWLV KFVLLPKFFH YKLLPKITYL HDGLIVTEWV 
541:	KKPCLC