TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.3.8.8
Aspartate/glutamate Na+-independent transporter, AGT1

Accession Number:Q91WN3
Protein Name:AGT1 aka 0610009O04RIK aka XAT2
Length:478
Molecular Weight:53233.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate aspartate, glutamate

Cross database links:

Genevestigator: Q91WN3
eggNOG: roNOG07130
HEGENOM: HBG714539
RefSeq: NP_083022.1   
Entrez Gene ID: 74087   
Pfam: PF00324   
KEGG: mmu:74087   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0006865 P:amino acid transport
GO:0055085 P:transmembrane transport

References (5)

[1] “Homologues of amino acid permeases: cloning and tissue expression of XAT1 and XAT2.”  Blondeau J.-P.et.al.   11943479
[2] “Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family associated with unknown heavy chains.”  Matsuo H.et.al.   11907033
[3] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[4] “Lineage-specific biology revealed by a finished genome assembly of the mouse.”  Church D.M.et.al.   19468303
[5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MAMDSKKEIR LKRELGYFWG TNFLIINIIG AGIFVSPKGV LQHSSMNVGV SLCVWAVCAV 
61:	LTLTSALCSA EIGITFPYSG AHYYFLKRCF GPLVAFLRLW TSLFLGPGLI ASQALLLAEY 
121:	GVQPFYPSCS APILPRKCLA LAMLWIVGIL NSRGVKELSW LQTVSSVLKV GILGVISLSG 
181:	LFLLVRGKKE NVQRLQNAFD AEFPEVSQLI EAIFQGYFAF SGGGCFTCIA GELKKPSKTI 
241:	PRCIFTGLPL VTVVYLLANI SYLTVLTPQE MLSSDAVALT WTDRVIPQFT WTVPFAISAS 
301:	LFINLVINVL ETSRVLYIAS ENGQLPLLFC ALNVHSSPFI AVLLIISMAS ILIVLTNLID 
361:	LINYLYFVVS IWTALSIIGI LKLRYQEPNL HRPYKVFLPF TFIALGITLS LVLIPLVKSP 
421:	KLHYIYVFLF LLSGLVFYVP LIHFKVKFVW FQKLTCYLQL LFNICIPDVS DDHIHEES