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2.A.30.1.19
K+,Cl--cotransporter, KCC or Slc12a5b of 1117 aas and 12 TMSs. Ion transport via an ortholog is oxygen-sensitive and is regulated by two different oxygen sensors in crucian carp (Carassius carassius) (Berenbrink et al. 2006).

Accession Number:E9QC71
Protein Name:Solute carrier family 12 (potassium/chloride transporter), member 5b
Length:1117
Molecular Weight:123156.00
Species:Danio rerio (Zebrafish) [7955]
Number of TMSs:11
Substrate

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMNNLNECEE GDGGPNSQGD ATSKESSPFI NSSTSDVEKS QQYDGKNMAL FEEEMDTSPM 
61:	VSSLLSSLAN YSNLTQGSKE HEEAENNEEA RKKAAQAPRM GTIMGVYLPC LQNILGVILF 
121:	LRMTWLVGVG GVLGTFTIVF MCCSTTMLTA ISMSAIATNG VVPAGGSYYM ISRSLGPEFG 
181:	GAVGICFFLG TTFAGAMYIL GCIEILLIYI VPSAAIFKME GLEGSEAEAA LLNNMRVYGT 
241:	IVLTFMAIVV FVGVKYVNKL ALVFLACVIL SILAIYAGVI KTSFDPPDFP VCVLGNRTLV 
301:	SKAYDICAKT IERGNATITT KLWRSFCDSE FLNATCDEYF VNNNISQIQG IPGVTSGILA 
361:	ENLFSGYMEK NSVLEKRGLQ AVQDPELPVT NSNRYVLADI TSFFTLLVGI YFPSVTGIMA 
421:	GSNRSGDLQD AQKSIPVGTI LAITTTSIIY MSSVILFGAC VDGVVLRDKF GEGVSGNLVI 
481:	GTLAWPSPWV IVFGSFFSTC GAGLQSLTGA PRLLQAIARD GIIPFLRVFG HGKANGEPTW 
541:	ALLLTACICE SGILIASLDA VAPILSMFFL MCYMFVNLAC ALQTLLRTPN WRPRFKFYHW 
601:	ALSLLGMSLC LTLMFLCSWY YAIVAMVIAG CIYKYIEFCG AEKEWGDGIR GISLSAARFA 
661:	LMRLEEGPPH TKNWRPQILV LTTLDGEQNV EQPRLLSLTS QLKAGKGLTI VGACIEGTYL 
721:	NNQPKTQKAD QSLRKLMEVE KVKGFSQVVI SSNLRDATSH LIQAGGLGGL RHNTVLVSFP 
781:	KNWKQAEEHH RCRNFIEVVR ETTAGHMALL VPKNISAYPS NGERFTEGHI DVWWIVHDGG 
841:	MLMLLPFLLR QHKVWRKCKM RIFTVAQMDD NSIQMKKDLM TFLYHLRLDA AVEVVEMLDN 
901:	DISAYTYEKT LMMEQRSQIL KEMHLTKNER EREIQSITDV SRGSIRRKNP SNLHPQRSIA 
961:	EESVAGSGEE KPEEEVQLIQ GKNATPTPTS PTSPTAPTPA TMSPGEEIQM TWTDDTEKAN 
1021:	NPAVANPENI KDMFNMKPEW ENLNQSNVRR MHHAQKLNEV IVKKSQEAKL VLLNMPGPPR 
1081:	NRTGEENYME FLEVLTEGLN RVLLVRGGGR EVITIYS