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2.A.35.1.3
The putative tyrosine permease, TyrT, of 472 aas and 12 TMSs.  Also called NhaC2 (Panina et al., 2003; Rodionov et al. 2004).

Accession Number:Q838N7
Protein Name:TyrT aka NhaC-1
Length:467
Molecular Weight:49916.00
Species:Enterococcus faecalis (Streptococcus faecalis) [1351]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate tyrosine

Cross database links:

HEGENOM: HBG307651
RefSeq: NP_814191.1   
Entrez Gene ID: 1199320   
Pfam: PF03553   
KEGG: efa:EF0402   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015385 F:sodium:hydrogen antiporter activity
GO:0006885 P:regulation of pH
GO:0006814 P:sodium ion transport

References (1)

[1] “Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.”  Paulsen I.T.et.al.   12663927

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKEKQKKKTV SVREASIVLL IIVAAIATGV IGLKISPNIT ILFVIALILG YAMFRKVPFD 
61:	QMHKGIVDGL KPGIIPIFIF ILVGALIAVW IQAGIIPTIM VFGFKMISVK WFVPSVFIVC 
121:	AIVGSAVGSA FTVMSTIGIA FFGIGSTLGL NPALVVGAIV SGSVFGDKMS PLSESTNLAA 
181:	AIVEADLFKH IKNLMWSTVP AFIVSLILFM ILGQTYANTS LTEVVQVIQV LEDHFTISIW 
241:	SLLPLALMLI CAWRKIPAII TILLNIIVAV IMIIIQNPKV SLQALGNTLE NGFVSQTGNA 
301:	QIDQLLSRGG IMSMMPTVAL IILTLSLGGL LMELGLISAV MEVVSQKMSS TPKLILSTLL 
361:	TGIGVNIFIG EQFLSVILPG NAFKEVYKKE GLDPTVLGRT LEDGGTVINY LIPWGIAGSF 
421:	VAGTFGVPTL TYLPFVFFSL LSPVFSMVSA FTGLGIKRLS AEPVTEK