TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.35.1.4
The arginine/ornithine antiporter ArcD (Wimmer et al. 2008)

Accession Number:B0R9X2
Protein Name:Arginine/ornithine antiporter
Length:485
Molecular Weight:50523.00
Species:Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1) [478009]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Arginine, Ornithine

Cross database links:

HEGENOM: HBG307651
RefSeq: YP_001690686.1   
Entrez Gene ID: 5954935   
Pfam: PF03553   
KEGG: hsl:OE5204R   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015385 F:sodium:hydrogen antiporter activity
GO:0006885 P:regulation of pH
GO:0006814 P:sodium ion transport

References (1)

[1] “Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1.”  Pfeiffer F.et.al.   18313895

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MVEFEPRSYE DFDPEKRPSF GQALLPIAGM ITFLAVGIVL LGLDAQMPLL WGIAFTGVIA 
61:	RYGWGYTWDE LFDGISNSIV MGLGAIFILF IIYMLIASWV DAGTIPFIMY WGLEFLTPAV 
121:	FVPLAALLSF VVATAIGSSW TTAGSLGIAL VGIGSGLGIP APLTAGAILS GVYMGDKQSP 
181:	LSDTTLLASG VSDVDLWDHV RGMFPNTIIV GVISLALYAV LGLMAETGGT GGTGAEVAQI 
241:	QGGLAGTYTL SVLVLLPLVI TFGLAIKGYP ALPSLGAGVF SAAGVSILIQ GRGFAEAWQI 
301:	IYSGTGPKTG VDLVNNLLST GGLEGSIWVI TIVFGALSIG GILEATGVLS VIAHNTAKAV 
361:	DSVGGATLVT ALGPLVINAL TADQYMSIVI PGMTFRDLND EYDLDGTSLS RTLEETGTVS 
421:	EPMIPWNSGG VFMASALGVP VLSYLPYYFV GILSPILVVI MGFTGWKMYM KDPEESPEES 
481:	ADTAA