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2.A.36.1.10
Basal membrane Nhe3

Accession Number:Q17L17
Protein Name:Nhe3
Length:1179
Molecular Weight:130187.00
Species:Aedes aegypti (Yellowfever mosquito) [7159]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cytoplasmic vesicle1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

RefSeq: XP_001653402.1   
Entrez Gene ID: 5570922   
Pfam: PF00999   
KEGG: aag:AaeL_AAEL00   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015385 F:sodium:hydrogen antiporter activity
GO:0006885 P:regulation of pH
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Genome sequence of Aedes aegypti, a major arbovirus vector.”  Nene V.et.al.   17510324

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MVAHSLQQEV NLSRRACRIP KWPLSGAQQE EENDEEVLEE QLLNGANQSP ASEVAAFRLG 
61:	PVHSENSPGG IDEDPLSFRN RRMHDGRMGS VVDFSCDLVA RVFLLVKALV MGVLRFDLTS 
121:	PKRASSSSSS SSSYGSQFSK NLVKWCTWAI VLSVLLANHG GFVLARPKNG VVTADGVDAA 
181:	SVASGQWELL TPQPVSSDGA VGGQISGSLS SVKQQDDQSH GGELGDASHG EGHEVERYPV 
241:	AQVEFSRVET PFVIGVWILS ASIAKIGFHM TPKLSKIFPE SCLLIVVGVI IGVLLRYATN 
301:	LHVSPLTPNT FFFYMLPPII LDAGYFMPNR MFFDNIGTIL LMAVIGTIFN IATIGVSLWA 
361:	CGLTGIFGVD LPFLHVFLFS SLISAVDPVA VLAVFEEIHV NEVLYIVVFG ESLLNDAVTV 
421:	VMYHMFESYN EIGASNIQVV DIVSGVASFF VVALGGTIIG VIWGFLTGLV TRFTDHVRVI 
481:	EPIFIFVMAY LAYLNAEIFH MSGILAITFC GITMKNYVEQ NVSHKSHTTI KYALKMLSSS 
541:	AETIIFMFLG VATVNNRHIW NTWFVILTIV FCSVFRIIGV LILSAMANRF RIHKLSKVDQ 
601:	FVMSYGGLRG AVAFALVLLV STDHIPLQPM FVTTTIAVIY FTVFLQGITI KPLVRVLNVK 
661:	RANKRKPTMN ERIHERFMDH TMAGIEDIVG KTGNYNIRDK FKRFDNRFIR PYLIKNLQGP 
721:	EPKILETYSK LTMRDAMDYM RRNPSTIGQM SGTESMSALF RNYTGVFGGS PSFSNLENST 
781:	RNLDMQELDY NPSKKDLTDA RIHHLLSVEL KPYRRTRRLS YSRHAVDDRD LSTQVNYKMQ 
841:	MNIRRMISEK KHKRSKRGKD GKTQNHVSFP ELPQNGSAKQ FANDYINEVL HEDNEDEDKL 
901:	PTAAGDDWDG GGLTFTAKSS LDEKSEQPKS DKRMSKDLRD LEAAENRVTT PTAIEAVLPW 
961:	KRVDEDDENG AIKQNEFPSW ASNKEYLAYN SPSATFLGGL TQPKQAKSVI GLFRRESSGS 
1021:	GGIVIGGVTD SEASTPVTAT TPIGRAKKDK RSASIAGYIT FPGSSDAGDD PLGVSRAVVS 
1081:	HANAFPVTAS HRRNNRRGSL LELSGEAIPE ENYSKSLPDR DKHGPRRGPT LIKASGTPKP 
1141:	ARNSKSNNPQ TTALLSSSST DSEEEEEEDK DCADEQHPI