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2.A.36.1.20
Endomembrane (Golgi) K+, Na+/H+ exchanger 5, NHX5, of 521 aas and 11 TMSs.  Three acidic residues are critical for transport activity as well as seedling growth, regulation of protein transport into vesicles and ionic homeostasis (Qiu 2016). NHX6 is 80% identical to NHX5 (535 aas and 11 TMSs) and serves the same function.

Accession Number:Q9SLJ7
Protein Name:Sodium/hydrogen exchanger 5
Length:521
Molecular Weight:57335.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Endosome membrane1 / Multi-pass membrane protein2
Substrate K+, H+, Na+

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEEVMISPVE HDPQGQVKQQ QAAGVGILLQ IMMLVLSFVL GHVLRRHRFH YLPEASGSLL 
61:	IGLIVGILAN ISDTETSIRT WFNFHEEFFF LFLLPPIIFQ SGFSLQPKPF FSNFGAIVTF 
121:	AIIGTFVASV VTGGLVYLGG SMYLMYKLPF VECLMFGALI SATDPVTVLS IFQDVGTDVN 
181:	LYALVFGESV LNDAMAISLY RTMSLVNRQS SSGEHFFMVV IRFFETFAGS MSAGVGVGFT 
241:	SALLFKYAGL DTENLQNLEC CLFVLFPYFS YMLAEGVGLS GIVSILFTGI VMKRYTFSNL 
301:	SEASQSFVSS FFHLISSLAE TFTFIYMGFD IAMEQHSWSH VGFILFSILF IGVARAVNVF 
361:	GCAYLVNLFR QENQKIPMKH QKALWYSGLR GAMAFALALQ SLHDLPEGHG QIIFTATTTI 
421:	VVVTVLLIGG STGKMLEALE VVGDDLDDSM SEGFEESDHQ YVPPPFSIGA SSDEDTSSSG 
481:	SRFKMKLKEF HKTTTSFTAL DKNFLTPFFT TNSGDGDGDG E