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2.A.36.1.6
Zebrafish Na+:H+ antiporter NheC (Yan et al., 2007) (most similar to TC# 2.A.36.1.2, 48% identical)

Accession Number:A3KPJ8
Protein Name:NheC
Length:851
Molecular Weight:94380.00
Species:Danio rerio (Zebrafish) (Brachydanio rerio) [7955]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+, H+

Cross database links:

eggNOG: fiNOG07234
HEGENOM: HBG444842
Pfam: PF00999   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015385 F:sodium:hydrogen antiporter activity
GO:0006885 P:regulation of pH
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MAFSTLLLAF LVVSGALHEA AAGLDFYGAE GKQNYSSRSS AEGSASSGNS SHSATITTLP 
61:	IVTWKWHHVE TPYLVALWIL TCWLCKLVTE LNHNITSVIP ESGLLIILGF ILGGIVWGAD 
121:	KAQTFKLIPV NFFYYLLPQI ILDASYCMPN KLFFGNLGAI LVHAIIGTCW NAGTVGIALW 
181:	ACYEGGAMGT LNIGCLQFLL FGALMSAVDP VAVIAVFEEV HVNEVLYILV FGESLLNDGV 
241:	TVVLYNVFDA FVSLGGPKIN AAEIIKGIVS FAVVAFGGSF LGVVFAVLTS MLTRVTKNVQ 
301:	IIEAGFIIVL GYLSYLTAEM LSLSAILSLT FCGVCCQKYI NANMDEKSVT CLRYSLKVLA 
361:	NGSETMIFVF LGVSAIDQTI WVWNTGFILL TLLFIVVFRM MGVFFLNWIL NQSRLIPIDL 
421:	TDQLVMGYGG LRGAVAYGLA ASLDENKIPE KNLMLGTTLI VVYFTVILQG ITMKPLVNWL 
481:	KVKKATQSDL TLNGKLNNRV FEHTLTGMED ICGRMGDNWW TRHWNHFEEK YVCWLLMTSE 
541:	ARKRNDKILD AFHKLNVEDA TKYVNEGESK GSLAFIRSYD SASVDFKKKL ALEYADIIPD 
601:	IMADMSEYDF DIDSVPVTSV MKNPIPSVSL DIHEQERRGM SNDLNAHHLL EQHLYKSRRN 
661:	NRATYSRSHY NTSENPDEMQ EIFQRTMRNR LESFKSAKMG VNPAKKVSKH PKKDAPHKPN 
721:	GKPADPNRDH LYGDEDFEFS ADSASSSENT GQFPRRVINT TGAGVDNPAY IPELDTSPSM 
781:	RNPPWQTETG HNTAVAPSQR AQGRLPWTPT NLRRLAPLRV SSRSTDSFAM PEPAADEETP 
841:	EEKPATHHTR L