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2.A.36.3.1
Putative antiporter of 549 aas (function unknown) (Verkhovskaya et al. 2001).

Accession Number:P32703
Protein Name:YjcE aka B4065
Length:549
Molecular Weight:60523.00
Species:Escherichia coli [83333]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Genevestigator: P32703
EchoBASE: EB1884
EcoGene: EG11940
eggNOG: COG0025
HEGENOM: HBG648988
RefSeq: AP_004566.1    NP_418489.1   
Entrez Gene ID: 948577   
Pfam: PF00999   
BioCyc: EcoCyc:YJCE-MONOMER    ECOL168927:B4065-MONOMER   
KEGG: ecj:JW4026    eco:b4065   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015299 F:solute:hydrogen antiporter activity
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.”  Blattner F.R.et.al.   8265357
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEIFFTILIM TLVVSLSGVV TRVMPFQIPL PLMQIAIGAL LAWPTFGLHV EFDPELFLVL 
61:	FIPPLLFADG WKTPTREFLE HGREIFGLAL ALVVVTVVGI GFLIYWVVPG IPLIPAFALA 
121:	AVLSPTDAVA LSGIVGEGRI PKKIMGILQG EALMNDASGL VSLKFAVAVA MGTMIFTVGG 
181:	ATVEFMKVAI GGILAGFVVS WLYGRSLRFL SRWGGDEPAT QIVLLFLLPF ASYLIAEHIG 
241:	VSGILAAVAA GMTITRSGVM RRAPLAMRLR ANSTWAMLEF VFNGMVFLLL GLQLPGILET 
301:	SLMAAEIDPN VEIWMLFTNI ILIYAALMLV RFGWLWTMKK FSNRFLKKKP MEFGSWTTRE 
361:	ILIASFAGVR GAITLAGVLS IPLLLPDGNV FPARYELVFL AAGVILFSLF VGVVMLPILL 
421:	QHIEVADHSQ QLKEERIARA ATAEVAIVAI QKMEERLAAD TEENIDNQLL TEVSSRVIGN 
481:	LRRRADGRND VESSVQEENL ERRFRLAALR SERAELYHLR ATREISNETL QKLLHDLDLL 
541:	EALLIEENQ