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2.A.36.4.5
Probable Na(+)/H(+) antiporter C3A11.09

Accession Number:O14123
Protein Name:Probable Na(+)/H(+) antiporter C3A11.09
Length:759
Molecular Weight:85487.00
Species:Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [284812]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+, H+

Cross database links:

eggNOG: COG0025
HEGENOM: HOG000168542
Entrez Gene ID: 2542509   
Pfam: PF00999   
KEGG: spo:SPAC3A11.09   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015079 F:potassium ion transmembrane transporter activity
GO:0015385 F:sodium:hydrogen antiporter activity
GO:0030007 P:cellular potassium ion homeostasis
GO:0071435 P:potassium ion export

References (2)

[1] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360
[2] “Phosphoproteome analysis of fission yeast.”  Wilson-Grady J.T.et.al.   18257517

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAWSQVEISK PHLAYAIIGG FTSLFMLCSL IIKEKLFLGE ATMATATGLI FGPYVAKLFV 
61:	PTSWGNTDYI TEELARVLLV VEVFAAGAEL PRAYMLRHWR SMFVMLLPVM IFGWLVSTGF 
121:	MYALIPRLSF LESLAIAACI TATDPVLASS IVGKGKFARR VPGHLRNMLL AESGCNDGMA 
181:	IPFLYLAIYL IIEKPARHAG RDWVCIIILY ECTFGCVLGA IIGVIARKMI KFSERRGLMD 
241:	RESFLVFYFV LALFCGGIGT IIGVDDLLVS FCAGAAFSWD SWFSKKTEES HVSNVIDLLL 
301:	NLSFFVYVGA IMPWPQFHMP HMDLSVWRLV VLAICILIAR RIPAVLLFKS FVPDIINWRE 
361:	ALFAGHFGPI GVGALYTCLV ARAELEVHST VPEPNDAIEN PEIPNWYCIQ VMWPVVCFLV 
421:	LSSIIVHGSS IAFFMLGKRI NTLALSFTRT RDSHFAFNLP RVRQGQSLPI KRVDALRSSA 
481:	NSIASSIRRR HPVNIQEDED ADISTVSLPE AAHLREERAE SPRGGHYDAE EFPSEDYESR 
541:	QPRRSNEEDR EEEMNPGDET YLIGEDLVVE DSQGNIISHT SSRDANGPSI DEKLAQGDPK 
601:	AKSFGRKFRS FLRRSYDTFQ RNLHEPDDER QREPTLGHIE SSIENHRPRY SRQNSESHLR 
661:	ENSVERRRRE QVLTNIGDSE SEDDNIPRPG IVPFYNENNE SSSDTRNGLL SDNVSESRSR 
721:	RPSRAPSAAV SSEGSPVEED NEAQHRPNIR FLELTRAWE