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2.A.36.6.11
Na+/H+ antiporter, NhaP2 (YcgO; CvrA) of 578 aas and 13 TMSs. Involved in growth at low osmolarity, intracellular K+ maintenance, and volume regulation (Verkhovskaya et al. 2001).

Accession Number:P76007
Protein Name:K(+)/H(+) antiporter NhaP2
Length:578
Molecular Weight:62285.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Na+

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDATTIISLF ILGSILVTSS ILLSSFSSRL GIPILVIFLA IGMLAGVDGV GGIPFDNYPF 
61:	AYMVSNLALA IILLDGGMRT QASSFRVALG PALSLATLGV LITSGLTGMM AAWLFNLDLI 
121:	EGLLIGAIVG STDAAAVFSL LGGKGLNERV GSTLEIESGS NDPMAVFLTI TLIAMIQHHE 
181:	SNISWMFIVD ILQQFGLGIV IGLGGGYLLL QMINRIALPA GLYPLLALSG GILIFSLTTA 
241:	LEGSGILAVY LCGFLLGNRP IRNRYGILQN FDGLAWLAQI AMFLVLGLLV NPSDLLPIAI 
301:	PALILSAWMI FFARPLSVFA GLLPFRGFNL RERVFISWVG LRGAVPIILA VFPMMAGLEN 
361:	ARLFFNVAFF VVLVSLLLQG TSLSWAAKKA KVVVPPVGRP VSRVGLDIHP ENPWEQFVYQ 
421:	LSADKWCVGA ALRDLHMPKE TRIAALFRDN QLLHPTGSTR LREGDVLCVI GRERDLPALG 
481:	KLFSQSPPVA LDQRFFGDFI LEASAKYADV ALIYGLEDGR EYRDKQQTLG EIVQQLLGAA 
541:	PVVGDQVEFA GMIWTVAEKE DNEVLKIGVR VAEEEAES