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2.A.36.7.3
Li+/H+ antiporter, AtNHX8 (An et al., 2007).  An orthologue in Puccinellia tenuiflora (alkali grass) is up regulated under salt stress and confers tolerance to high NaCl stress (Wang et al. 2011).

Accession Number:Q3YL57
Protein Name:NHX8
Length:756
Molecular Weight:83476.00
Species:Arabidopsis thaliana GN=NHX8 PE=2 SV=1 [3702]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Li+, H+

Cross database links:

Genevestigator: Q3YL57
eggNOG: KOG1965
HEGENOM: HBG589519
RefSeq: NP_172918.2   
Entrez Gene ID: 838028   
Pfam: PF00999   
KEGG: ath:AT1G14660   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0010348 F:lithium:hydrogen antiporter activity
GO:0010352 P:lithium ion export
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MTSIIGAALP YKSPEKAIAS SSYSAENDSS PVDAVIFAGT SLVLGTACRY LFNGTRVPYT 
61:	VVLLVIGIFL GSLEYGTKHN LGKLGHGIRI WNGINPDLLL AVFLPVLLFE SSFSMDVHQI 
121:	KRCMGQMVLL AGPGVLISTF CLGALIKLTF PYNWDWKTSL LLGGLLGATD PVAVVALLKE 
181:	LGASKKMTTL IDGESLMNDG VSVVVFQLFF KMVMGHNSDW GSIIKFLVQN SFGAVGIGLA 
241:	FGIASVFWLK FIFNDTVAQI TVTLSASYFA YYTAQEWAGV SGILTVMILG MFFAAFARTA 
301:	FKGDSHQSLH HFWEMAAYIA NTLVFMLSGV IIAESVLSGQ TISYKGNSWS FLFLLYLYVQ 
361:	LSRCVVVGVL YPLLCRSGYG LDWKESIILT WSGLRGAVSL SLALSVKQSS GNSYLSSDTG 
421:	TRFLFLTGGI VFLTLVVNGS TTQLLLHLLR MDTLTATKKR ILEYTKFEMM KTALKAFENL 
481:	GDDEELGSAD WPTVIRHISS LKDLEGRQVN PHDGYEAGSL DPTNIMDIRI RFLNGVQAAY 
541:	WEMLDDGRIT QCTANVLMQS VDEALDLVST SSLSDWRGLE PRVHFPNYYK FLQSKIIPHK 
601:	LVTHLIVERL ESACYISSAF LRAHRIARQQ LHIFLGNSNI ASTVINESEV EGEEAKQFLE 
661:	DVRDSFPQVL SVLKTRQVTH YVLNHLNGYI KNLEKVGLLE GKEVSHLHDV VQSDLKKLLR 
721:	HPPSLKLPNV DDLITSNPLL KDRSSFRSLA IGETDA