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2.A.36.7.7
Testis-specific sodium:proton exchanger, mtsNHE (Slc9c1) of 1175 aas and 12 - 16 TMSs.  It is present in sperm flagellae and seems to be required for optimal sperm motility, fertilization and the acrosome reaction (Liu et al. 2010).  69% identical to the human NHE, TC# 2.A.36.7.5.  It may have a 12 TMS topology, but has a long C-terminal hydrophilic domain with a segment showing 2 - 4 TMSs. 

Accession Number:Q6UJY2
Protein Name:Sodium/hydrogen exchanger 10
Length:1175
Molecular Weight:135545.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell projection1 / Multi-pass membrane protein2
Substrate Na+, H+

Cross database links:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEMEEISENL TASHSIKLTN MWLELLKSVF LSTPQDLPEI ILILSLICTV GAFLNMHLKD 
61:	FPIPLPVILF LIGCCFEILS FASTQIQIYA DAIQWMDPDI FFGIFTPVII FNVAFDMDIY 
121:	MLQKLFWQIL VITIPGFLIN YTLILWYLQS VNKLSLKTVP WLLFSAVLIS SDPMLTSASI 
181:	RDLGLSRSLT NLINGESLLT SVLSLVIYSG VVHIRFKSKS VNHTLAHKVM STAWSYIVES 
241:	FITGIVFTKV IQLWMATIFG DDVNHITLIF SVLYLIFYVC ELVGMSGIFT LATIGLFLNS 
301:	TSFKPGVEAF LLEFWNCLSF IGFLMVFTFI GLLIPAHTYL HISFSDVYYS LNIYFTLIVL 
361:	RLLVFLLMSP ILSRLGHGFS WRWAFIMVWS EMKGTPNINM ALLLAYSDIS LGSERERSQI 
421:	LFHGVSVCVI TLIVNRFILP MAVTKLGLRD VTSTKYKSVY YTFQHFQELT KSTAMALKFD 
481:	KDLANADWNM VDNAIILQNP YAMNQEEITE HQKVKCPDCN KEIDETLNIE AMELTNRRLL 
541:	SAQIASYQRQ YRNEVLSQSA VQVLVGAAGS FGEKKGEYMS PENIKNFSES KKLLSFLRKL 
601:	LLNWVYNTKK DKGVPSRYMF LHACHRIVFT NEFEYTGYLV VLMSTYPMII CWISRLKDIY 
661:	DNEIKCANYY FLAFYILEAL LKVAAMRKEF FSHTWLLFEL GITLVGVLDI ILIETDSISY 
721:	NFDLTETVVF MNVIRLLRIL RILKLVTPKL LQIIDKRMSQ QISFRYSILK GYVQGEMDVL 
781:	NIIDQIASSK QTKQILLKRV MRNMEHAMKE LGYLEYDHPE IAVTMKTKEE INVMLNMARE 
841:	IVKAFRSKGI IHKVEGTEIN KLIMAKKIQV LDLQSVIQPF NVEEAPCNIP WLSEDPEAIT 
901:	FIQEKAKVVT FDCGNNIFEE GDEPEGIYVI ISGMVKLKRS KPHLEMERVS AESEIKIHPL 
961:	PHTEYLLSGE IIGELNCLTK ERMQYSATCK TVVETYFIPI SHLYEGFEKR CPNMKHKMWQ 
1021:	KIGLAITAQK IREHLSFEDW NYKLQLKLCN AFIRDIPKSM KTDIYDETVT HVVLIHGSAE 
1081:	DCQLRKIYKA PFLIPVTCHQ IQGMEDFTKV MIIQTSIAVR KFRWNVRKYI PPRRISMKPD 
1141:	SERESFETLD ETSEEDNGKK ENQENEELIE ENINI