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2.A.37.1.4
K+ efflux antiporter 1, chloroplastic (AtKEA1).  Localizes to the chloroplast inner envelope membrane and is essential for normal osmoregulation (Kunz et al. 2014).

Accession Number:Q9ZTZ7
Protein Name:K(+) efflux antiporter 1, chloroplastic
Length:1193
Molecular Weight:128033.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Plastid1 / Multi-pass membrane protein2
Substrate H+, K+

Cross database links:

Genevestigator: Q9LQ76
eggNOG: COG1226
HEGENOM: HOG000100760
Entrez Gene ID: 837332   
Pfam: PF00999    PF02254   
KEGG: ath:AT1G01790   

Gene Ontology

GO:0031969 C:chloroplast membrane
GO:0016021 C:integral to membrane
GO:0000166 F:nucleotide binding
GO:0015299 F:solute:hydrogen antiporter activity
GO:0006813 P:potassium ion transport

References (7)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “Phylogenetic relationships within cation transporter families of Arabidopsis.”  Maeser P.et.al.   11500563
[3] “Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.”  Froehlich J.E.et.al.   12938931
[4] “Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.”  Ferro M.et.al.   12766230
[5] “The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.”  Kleffmann T.et.al.   15028209
[6] “Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.”  Zybailov B.et.al.   18431481
[7] “Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.”  Reiland S.et.al.   19376835

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEYASTFQRP ILFHGGDGAS YCFPNRLISP KGISITSGDS KVHSCFRLRR NVAQSGTLNL 
61:	MNACFSGRFY SGHLHSTKSI LGNGHQAKRI PFGFRLRCQG HESLGNADSN DHRIGESSES 
121:	SDETEATDLK DARVENDTDS LEELKELLHK AIKELEVARL NSTMFEEKAQ RISERAIALK 
181:	DEAATAWLDV NKTLDVIRDT VYEEALAKEA VQTATMALSL AEARLQVIVE SLEAGAGNDI 
241:	PHVSEETEET IDVNDKEEAL LAAKDDIKEC QVNLDNCESQ LSALLSKKDE LQKEVDKLNE 
301:	FAETIQISSL KAEEDVTNIM KLAEQAVAFE LEATQRVNDA EIALQRAEKS LSISQTPEET 
361:	QGQLSDEETS QEDAMVLSGN VEDVTHQVEK ESPKDGDLPV VQITAELVPD IVGQRNKKLT 
421:	QPYESSDHEN GKPSVESSKV VEADSEKPKI NVQTKKQETQ KDLPKEGSSL NSPKASFNKS 
481:	SRFFSASFFS SNPDGTATVF GSLVGSVKQQ WPKLVLGLAL LGAGLTLYSN GVGGNNQLLQ 
541:	QPDVTSTSTE DVSSSTKPLI RQVQKLPKRI KKLLEMIPHQ EVNEEEASLF DFLWLLLASV 
601:	IFVPLFQKIP GGSPVLGYLA AGILIGPYGL SIIRNVHGTR AIAEFGVVFL LFNIGLELSV 
661:	ERLSSMKKYV FGLGSAQVLV TAAVVGLLAH YVAGQAGPAA IVIGNGLALS STAVVLQVLQ 
721:	ERGESTSRHG RASFSVLLFQ DLAVVVLLIL IPLISPNSSK GGIGFQAIAE ALGLAAVKAA 
781:	VAITAIIAGG RLLLRPIYKQ IAENRNAEIF SANTLLVILG TSLLTARAGL SMALGAFLAG 
841:	LLLAETEFSL QVESDIAPYR GLLLGLFFMT VGMSIDPKLL LSNFPVIVGT LGLLIVGKTM 
901:	LVVIMGKLFG ISIISAIRVG LLLAPGGEFA FVAFGEAVNQ GIMSPQLSSL LFLVVGISMA 
961:	ITPWLAAGGQ LIASRFELHD VRSLLPVESE TDDLQGHIII CGFGRVGQII AQLLSERLIP 
1021:	FVALDVSSDR VTIGRSLDLP VYFGDAGSKE VLHKIGAGRA CAAVVALDAP GANYRCVWAL 
1081:	SKFYPNVKTF VRAHDVVHGL NLEKAGATAV VPETLEPSLQ LAAAVLAQAK LPTSEIANTI 
1141:	NEFRTRHLSE LTELCEASGS SLGYGYSRTS KPKPQPSDAS GDNQIIEGGT VVI