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2.A.37.1.6
K+ efflux - K+:H+ antiporter 3 (AtKEA3) of 776 aas and 13 TMSs.  Localizes to the thylakoid membrane of the chloroplast.  It modulates pmf partitioning through H+ efflux from the lumen, which is critical for photosynthetic acclimation after transitions from high to low light intensity (Armbruster et al. 2014; Kunz et al. 2014).

Accession Number:Q9M0Z3
Protein Name:K(+) efflux antiporter 3, chloroplastic
Length:776
Molecular Weight:83791.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Plastid1 / Multi-pass membrane protein2
Substrate H+, K+

Cross database links:

Genevestigator: Q9M0Z3
eggNOG: COG0475
HEGENOM: HOG000244181
Entrez Gene ID: 825822   
Pfam: PF00999    PF02254   
KEGG: ath:AT4G04850   

Gene Ontology

GO:0009507 C:chloroplast
GO:0031969 C:chloroplast membrane
GO:0016021 C:integral to membrane
GO:0000166 F:nucleotide binding
GO:0015299 F:solute:hydrogen antiporter activity
GO:0006813 P:potassium ion transport

References (4)

[1] “Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.”  Mayer K.F.X.et.al.   10617198
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “Phylogenetic relationships within cation transporter families of Arabidopsis.”  Maeser P.et.al.   11500563
[4] “Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.”  Zybailov B.et.al.   18431481

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAISTMLGSI SCCPSPKGYE MVKQHSVRLK HCVFTVKSSV PVYSEGVNDG IKLHSFGNLV 
61:	KKKVFLDTSK RFYFQGRWSE SSGRRVETYA GVDVASAVDV INDLGFDTLT FLMVTVIIVP 
121:	AFRILKASPI LGFFFAGVVL NQFGLIRNLT DVKVLSEWGI LFLLFEMGLE LSLARLKALA 
181:	KFAFGMGLTQ VLLCTAAFTA FELPPNGAIG TKILEFLFHS RPDLVNIRSI DEAVVIGAAL 
241:	SLSSSAFVLQ LLAEKGELPT RFGSATLGIL LLQDIAVVPL LVILPVLESQ DIGGESIWPM 
301:	LAKESAKALG GLGILSLGGK FFLRRIFEVV AETRSSEAFV ALCLLTVAGT SLVTQWLGFS 
361:	DTLGAFLAGA LLAETNFRTQ IEADIRPFRG LLLGLFFVTT GTSIDMEVLF REWPNVLSLL 
421:	GGLIVIKTLI ITAIGPRVGL TIQESVRVGF LLSQGGEFAF VVFSLANRLG VLPNELNKLL 
481:	IIVVVLSMAL TPYLNQLGRK AADFLDERLD PGEKIGEDVN FDVSESIVII GFGQMGQVLA 
541:	NFLSTPLVSD SDLVGWPYIG FDLNPAVVKE SRKLGFPILY GDGSRPSVLQ SAGVSSPKAI 
601:	MIMYKGKKRT TEAVQRLRLA FPGSPIYARA QDLPHLLELK KAGATDAILE NAETSLQLGS 
661:	KLLTGFGVMS DDVSFLSKVF RDSMEIQAQE EITASETNAG LKPMQMKASD INVVSAATQK 
721:	QVQLMKPMQM KASDSNSDSA AEILQETAGL SQPPEIDDSS VNIDNGFVGK ADKAQD