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2.A.37.2.2
The Na+/H+-K+ antiporter, GerN (spore germination protein-N) (Southworth et al., 2001).

Accession Number:Q9KI10
Protein Name:GerN
Length:387
Molecular Weight:41093.00
Species:Bacillus cereus [1396]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+, K+, H+

Cross database links:

Pfam: PF00999   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015299 F:solute:hydrogen antiporter activity
GO:0006812 P:cation transport
GO:0055085 P:transmembrane transport

References (1)

[1] “GerN, an antiporter homologue important in germination of Bacillus cereus endospores.”  Thackray P.D.et.al.   11133940

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEFEFFFQIA LILLSTKLAG DLSVRLGQPS VLGKLIVGIV IGPAVLGWIE NSELLTQLSN 
61:	VGVILLMFMA GLETDLEELN ANRNSSLAVA LGGIILPFVG GYVSGLVMGM EQGNAVFLGL 
121:	LLCATSVSIS VQTLRDLGKM KTRESTTMLG AAVFDDILVV ILLAFAMSFL GTDDVNLTMV 
181:	ILKKVVFFAS IILIGWKGVP AIMRWLSPLR VSESIVSAAL IICFSFAYFG ELLGIAGIIG 
241:	AFAAGIAISQ TNYKHEVEKK VEPIAYAMFV PVFFVSIGMN ITFDGIGNQI WFILALTVIA 
301:	VLTKLIGCGF GARMTGFDAK SSAIIGAGMV SRGEVALIIA GTGLSSGLLA QDYFTAIVIV 
361:	VILTTMITPP MLKYTFGAKD KAMKASK