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2.A.37.2.5
Na+/H+ exchanger of 732 aas.  The exchanger is the N-terminal domain, and the C-terminal domain is in the cl00292 superfamily of adenine nucleotide alpha hydrolases.  This superfamily includes N-type ATP PPases, ATP sulphurylases, Universal Stress Response proteins and electron transfer flavoproteins (ETF). The domain forms a apha/beta/apha fold which binds to adenosine nucleotides.

Accession Number:B3EE21
Protein Name:Sodium/hydrogen exchanger
Length:732
Molecular Weight:80179.00
Species:Chlorobium limicola (strain DSM 245 / NBRC 103803) [290315]
Number of TMSs:13
Substrate Na+, H+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFLNGLTEIT LPLKNPVLQF SLILFIILFV PFFLKRLRIP SLISLIIAGA VAGPHGLNLM 
61:	LRDSSIILFG TVGLLYIMFL AGLEIDVADF KKNSGKSILF GLYTFLISQL LGFFVALYVL 
121:	GFSLLSSVLI GSIFASHTLI VYPVVSRLGI AKDKAVNIAV GGTMITDTLA LLVLAVVAGS 
181:	SSGELTSAFW IRLFIGITIF SLIVLLLFPF IARWFFKRFD DSVLQYLFVL GMVFFAAFLA 
241:	EVAGVEAIIG AFLGGLSLNR LIPHTSALMN RIRFAGDAIF IPFFLIGVGM LIDFRAFFKD 
301:	AETIKVALVI TVAATVAKYF SAWITQKIYG FSVDQRRLIF GLISAHAAVA LATVLIGYNS 
361:	ITGYTLDGDP VRLLDKSVLN GTILFILVTC TLASIVGEKG AQNIAFAELA DEASSPDVHA 
421:	APERILIPMN DMKTVDELVN LGITIKSPKN RDGLFALHVA DSTSPGGAVE KHAEKLLEKA 
481:	VITAASTDND LTGVFRYDTS VANGIAGVAR EQRVTDIILG LHHKSSLADS FLGGLSEMLL 
541:	ATCNGTIFIY KPVQPLATIK RTIAVIPEGA ESEEGFIFWK DRLSNMVNNS SSKLIFYASK 
601:	QTLGYLKEYH SASFPNAEYK IFRTLDEFSG LAKEVRSDDN IVVVMSRRNY RSWHSRMAKI 
661:	PAYLGKYFGR NSFILIYPVQ SGGADESIAF SESRLSGGIQ FSMVPLRSQV ESMLKRVSFK 
721:	RISLRRNRKE PQ