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2.A.37.4.2
Endosome and prevacuole K+:H+ antiporter, CHX17.  Mediates potassium ion and pH homeomeostasis, thereby influencing membrane trafficking (Chanroj et al. 2011).

Accession Number:Q9SUQ7
Protein Name:Cation/H+ exchanger
Length:820
Molecular Weight:89166.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate K+, H+

Cross database links:

Genevestigator: Q9SUQ7
eggNOG: KOG1650
HEGENOM: HBG732777
RefSeq: NP_194101.1   
Entrez Gene ID: 828470   
Pfam: PF00999   
KEGG: ath:AT4G23700   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015299 F:solute:hydrogen antiporter activity
GO:0006812 P:cation transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.”  Mayer K.F.X.et.al.   10617198
[2] “Novel subsets of the Arabidopsis plasmalemma phosphoproteome identify phosphorylation sites in secondary active transporters.”  Hem S.et.al.   17869214
[3] “Expression patterns of a novel AtCHX gene family highlight potential roles in osmotic adjustment and K+ homeostasis in pollen development.”  Sze H.et.al.   15347787

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGTNGTTCPG PMKATSNGVF QGENPLEHAL PLLILQICIV LLLTRLLAFL LRPLRQPRVI 
61:	AEIVGGILLG PSALGKSTKF INTVFPPKSL TVLDTLANLG LIFFLFLVGL ELDPKSLKRT 
121:	GKRALSIALA GITLPFVLGI GTSFALRSSI ADGASKAPFL VFMGVALSIT AFPVLARILA 
181:	EIKLLTTDIG KIALSAAAVN DVAAWILLAL AVALSGEGSS PLTSLWVFLS GCGFVLFCIF 
241:	VVQPGIKLIA KRCPEGEPVN ELYVCCTLGI VLAASFVTDF IGIHALFGAF VIGVIFPKEG 
301:	NFANALVEKV EDLVSGLFLP LYFVSSGLKT NVATIQGAQS WGLLVLVIFN ACFGKIIGTV 
361:	LVSLYCKVPL DQSLALGFLM NTKGLVELIV LNIGKDRGVL NDQIFAIMVL MAIFTTFMTT 
421:	PLVLAVYKPG KSLTKADYKN RTVEETNRSN KPLCLMFCFQ SIMNIPTIVN LIEASRGINR 
481:	KENLSVYAMH LMELSERSSA ILMAHKVRRN GLPFWNKDKS ENNSSSSDMV VVAFEAFRRL 
541:	SRVSVRPMTA ISPMATIHED ICQSAERKKT AMVILPFHKH VRLDRTWETT RNDYRWINKK 
601:	VMEESPCSVA ILVDRGLGGT TRVASSDFSL TITVLFFGGN DDREALAFAV RMAEHPGISL 
661:	TVVRFIPSDE FKPENVRIEI TEDQLCSGAT RLIDIEAITE LKAKIKEKES SRSNSDSESH 
721:	IIYEEKIVKC YEEVIEVIKE YSKSNLFLVG KSPEGSVASG INVRSDTPEL GPIGNLLTES 
781:	ESVSTVASVL VVQQYIASRP VGISKNVTTE ESLVEDSESP