TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.37.4.7
Cation/H(+) antiporter 1 (Protein CATION/H+ EXCHANGER 1) (AtCHX1)

Accession Number:Q9SA37
Protein Name:Cation/H(+) antiporter 1
Length:785
Molecular Weight:88909.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate cations, H+

Cross database links:

Genevestigator: Q9SA37
eggNOG: COG0475
HEGENOM: HOG000239640
Entrez Gene ID: 838208   
Pfam: PF00999   
KEGG: ath:AT1G16380   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015299 F:solute:hydrogen antiporter activity
GO:0006813 P:potassium ion transport

References (3)

[1] “Expression patterns of a novel AtCHX gene family highlight potential roles in osmotic adjustment and K+ homeostasis in pollen development.”  Sze H.et.al.   15347787
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Phylogenetic relationships within cation transporter families of Arabidopsis.”  Maeser P.et.al.   11500563

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MDPKMLFCLP EGDALFNPLN TMFIQMACIL VFSQFFYLFL KPCGQAGPVA QILAGIVLSL 
61:	LTIIRKVHEF FLQKDSASYY IFFSFLLRTA FVFLIGLEID LDFMKRNLKN SIVITLGSLV 
121:	ISGIIWLPFL WFLIRFMQIK GDFLTFYLAF LITLSNTAAP VVIRSIIDWK LHTSEIGRLA 
181:	ISCGLFIEIT NIFIYTIVLS FISGTMTADI FIYSFATGVI ILTNRFLASW LPKRNPKEKY 
241:	LSKAETLAFI ILILIIALTI ESSNLNSTLF VFIIGLMFPR EGKTYRTLIQ RLSYPIHEFV 
301:	LPVYFGYIGF RFSVNSLTKR HYLVLGMTVA LSLLGKLLGV LFACSFLKIP KQYWLFLSTM 
361:	LSVKGHIGLV LLDSNLMYKK WFTPVVHDMF VAALVIMTLL SGVITSLLLR SQEKSFAHIK 
421:	TSLELFDTTE ELRVLTCVYG VRHARGSISL VSALSGFSPG TSSSPFTPYL MHLIPLPKKR 
481:	KTELLYHELD EDAGNSNGGD DEFGTNEGLE INDSIDSFTR DRKIMVRQVK LVAPMENMHE 
541:	EICNATEDLR VSIVFLPFHK HQRIDGKTTN DGEVFRHMNR KVLKQAQCSI GIFVDRNITG 
601:	FHQLHGSDSV QHVAALFFGG PDDREALSLC KWLTNNSQIH LTVIQFVADD SKTEKIVGDA 
661:	VTKENNEVFL EIVSEDQTEN ETDRIFLEEF YHRFVTTGQV GFIEKRVSNG MQTLTILREI 
721:	GEMYSLFVVG KNRGDCPMTS GMNDWEECPE LGTVGDFLAS SNMDVNASVL VVQRHRNSFD 
781:	SFVDE