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2.A.37.4.8
Endoplasmic reticular K+/H+ antiporter, CHX20.  Maintains pH and K+ homeostasis in guard cells. Plays a critical role in osmoregulation through the control of stomates opening.  Regulates alkaline pH-sensitive growth and influences membrane trafficking (Chanroj et al. 2011).

Accession Number:Q9M353
Protein Name:Cation/H(+) antiporter 20
Length:842
Molecular Weight:91553.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Endomembrane system1 / Multi-pass membrane protein2
Substrate K+, H+

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPFNITSVKT SSNGVWQGDN PLNFAFPLLI VQTALIIAVS RFLAVLFKPL RQPKVIAEIV 
61:	GGILLGPSAL GRNMAYMDRI FPKWSMPILE SVASIGLLFF LFLVGLELDL SSIRRSGKRA 
121:	FGIAVAGITL PFIAGVGVAF VIRNTLYTAA DKPGYAEFLV FMGVALSITA FPVLARILAE 
181:	LKLLTTQIGE TAMAAAAFND VAAWILLALA VALAGNGGEG GGEKKSPLVS LWVLLSGAGF 
241:	VVFMLVVIRP GMKWVAKRGS PENDVVRESY VCLTLAGVMV SGFATDLIGI HSIFGAFVFG 
301:	LTIPKDGEFG QRLIERIEDF VSGLLLPLYF ATSGLKTDVA KIRGAESWGM LGLVVVTACA 
361:	GKIVGTFVVA VMVKVPAREA LTLGFLMNTK GLVELIVLNI GKEKKVLNDE TFAILVLMAL 
421:	FTTFITTPTV MAIYKPARGT HRKLKDLSAS QDSTKEELRI LACLHGPANV SSLISLVESI 
481:	RTTKILRLKL FVMHLMELTE RSSSIIMVQR ARKNGLPFVH RYRHGERHSN VIGGFEAYRQ 
541:	LGRVAVRPIT AVSPLPTMHE DICHMADTKR VTMIILPFHK RWNADHGHSH HHQDGGGDGN 
601:	VPENVGHGWR LVNQRVLKNA PCSVAVLVDR GLGSIEAQTL SLDGSNVVER VCVIFFGGPD 
661:	DRESIELGGR MAEHPAVKVT VIRFLVRETL RSTAVTLRPA PSKGKEKNYA FLTTNVDPEK 
721:	EKELDEGALE DFKSKWKEMV EYKEKEPNNI IEEILSIGQS KDFDLIVVGR GRIPSAEVAA 
781:	LAERQAEHPE LGPIGDVLAS SINHIIPSIL VVQQHNKAHV EDITVSKIVS ESSLSINGDT 
841:	NV