TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.39.2.3
The hypoxanthine/adenine/guanine (purine) transporter, Fcy21 (Goudela et al., 2006)

Accession Number:Q708J7
Protein Name:Putative purine-cytosine permease aka Fcy21
Length:514
Molecular Weight:56496.00
Species:Candida albicans (Yeast) [5476]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Hypoxanthine, Adenine, guanine

Cross database links:

Pfam: PF02133   

Gene Ontology

GO:0016020 C:membrane
GO:0015205 F:nucleobase transmembrane transporter activity
GO:0015931 P:nucleobase, nucleoside, nucleotide and nucl...
GO:0055085 P:transmembrane transport

References (1)

[1] “Molecular mechanisms of primary resistance to flucytosine in Candida albicans.”  Hope W.W.et.al.   15504867

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MSSDPEKNLG MPEKTSVNSY DSMDPSSSSS GADAEIETTK LNFIDRWAHK LNAETKGIEL 
61:	VTDEEKTDTS FWNLATMWLS ANLVIATFSL GALGITVFGL AFGQAVLVII FFSILGGFPV 
121:	AFFSCFGSAL GLRQMLLSKF LIGDLTTRLF AAINVVACVG WGAVNTMSSA QLLHIVNNGT 
181:	LPPWAGCLII VVCTVLVTFF GYHVIHAYEK WAWIPNLIIF IIIIVRFAMT NKFTSKSFEG 
241:	GETTAGNVLS FGGTVFGFAT GWTTYSSDYV VYHPRNTNSW KIFFSIFFGL LTPLMFTLIL 
301:	GAACATGIAG DPEWTRLYKE DSVGGLVYAI LVHDSLHGFG QFCCVVLALS TVANNVPNMY 
361:	SMALSAQTVW AGFRKIPRVA WTIAGNGATL AICIPAYYKF EAVMENFMNL ISYYLSIYES 
421:	IMFASHFIWN SGRFDGYDYE RWNDKEAYPV GYAGVFGFAC GVAGVVLGMN QTWYSGVIGR 
481:	RIGEFGGDIG FELAIGFAFI GFNVARYFEK KYIR