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2.A.39.3.11
Purine/uracil uptake porter of 599 aas and 12 TMSs, NCS1 or PLUTO.  Nucleobase:proton symporter that facilitates the uptake of nucleobases in the cells. Can transport adenine, guanine and uracil (Witz et al. 2014). Contributes to uracil import into plastids for plastidic uracil salvage which is essential for plant growth and development (Witz et al. 2012).

Accession Number:Q9LZD0
Protein Name:Purine-uracil permease NCS1
Length:599
Molecular Weight:65356.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Plastid1
Substrate Uracil, Adenine, H+, guanine

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
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  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MVSNCLSLSL HLNLHPHKHN RHSLSSLRSR TKAKLYQHVS FTDSSHKSSY TSCVSTFDIQ 
61:	RKSSKHYELG KHSFSPILPG DNLVLSRSGV IRPRLSAMTG SEINDHGYDE SQFDPSLTND 
121:	DLKPTTPSQR TFSWLDMSSL WIGLVVGVPT YYLAGSLVDL GMAWWQGIAT VVTANLILLV 
181:	PLVLTAQPGT LYGISFPVLA RSSFGIRGAH IPTLLRALVG CGWYGIETWI GGEAIFLLLP 
241:	GHIKKSALSH TLPWLGTSPL EFSCFIVFWL AQLCIVWRGM DGIRKLEKYS APILISLTSC 
301:	LLAWSYLKAG GFGHMLSLSS KLTSAQFWTL FFPSLTANIS FWATLALNIP DFSRFAKSQT 
361:	DQIIGQVGLP VFMGLFTFVG VAVTSSTSII FGRVISNPIE LLGQIGGLAT TLLAIVGISL 
421:	ATLTTNIAAN VVAPANALVN LNPKFFTFGR GAFLTAVLGI VFQPWRLLKS SESFVYTWLI 
481:	GYSALLGPIG GIILVDYYLI KKMKLNIGDL YSLSPSGEYY FSKGYNVAAV VALVAGIIPV 
541:	VPGFLHKISA LSKISNGFVV VYDNALFFSF IIAGFVYWII MSRLGRKQSS LSSSSHPLL