TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.39.3.7
Uracil permease

Accession Number:Q10279
Protein Name:Uracil permease
Length:581
Molecular Weight:64177.00
Species:Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [284812]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Uracil

Cross database links:

eggNOG: COG1953
HEGENOM: HOG000202588
Entrez Gene ID: 2542586   
Pfam: PF02133   
KEGG: spo:SPAC1399.03   

Gene Ontology

GO:0005794 C:Golgi apparatus
GO:0016021 C:integral to membrane
GO:0045121 C:membrane raft
GO:0005886 C:plasma membrane
GO:0015505 F:uracil:cation symporter activity

References (3)

[1] “The uracil permease of Schizosaccharomyces pombe: a representative of a family of 10 transmembrane helix transporter proteins of yeasts.”  de Montigny J.et.al.   9730284
[2] “The genome sequence of Schizosaccharomyces pombe.”  Wood V.et.al.   11859360
[3] “Phosphoproteome analysis of fission yeast.”  Wilson-Grady J.T.et.al.   18257517

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MESVDNNSFF SRIRNSNAYR KVKDFVILDH RPGMTMAERM LTNKDLYPVP PSKRLWGPWN 
61:	FISFWLADAV NINTWMISAT AIELGLNWWE AWICVWVGYL ICGILVATTG RPGAVYHISF 
121:	PVLSRSSFGT WGSLWPILNR SVLACVWYGV QAWIGGECVV LMIRSIWPSF SHIPNTMAKS 
181:	GTETYQWVGF FIFWLLSNIA IWFPVHQIRH LFTFKAIVAP PAAIAFLIWA LVKAHGAGPV 
241:	IHEPTKLGQY EHAWVVINGI VTCIDGFATL IVNNPDFARF ATTPGAVHWP QIITVPLAFG 
301:	VTSLIGVLVS SASKAIYGTT LWDPTQLLAS FLDHSNAHGV RAGVFFIAFG LCIAQLGVNI 
361:	AANSVSAGND LSALLPTVIN VRRGGYIASI IALCMCPWNL LSSNNNFTTY LSSYSVFLSS 
421:	FAGVIIADYY FVRKGLIRVA PLYSSSSSSP YYFWKGINFR AFASYICGML INIVGMAGST 
481:	GQKVPKVANT MFNLNYFLGI TVACLSHIII CKIFPVTECG EKMLSEVPEE ADDYLLTLAS 
541:	EDSIDKDSTS EIYIDGLPTE KEVEKDDVLS ITSKKLSGCF P