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2.A.40.1.2
High affinity uracil permease (Martinussen et al. 2001).

Accession Number:Q9CF78
Protein Name:PyrP
Length:430
Molecular Weight:45312.00
Species:Lactococcus lactis (subsp. lactis) (Streptococcus lactis) [1360]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Uracil

Cross database links:

HEGENOM: HBG470187
RefSeq: NP_267759.1   
Entrez Gene ID: 1115263   
Pfam: PF00860   
BioCyc: LLAC272623:L46118-MONOMER   
KEGG: lla:L46118   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (1)

[1] “The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.”  Bolotin A.et.al.   11337471

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MHDNDIILKV DEKPAASQWF GLSFQHLFAM FGSTVLVPIL VGINPAIALL SSGLGTLAHM 
61:	SVTKFKVPAY MGSSFAYIGA MTLLMKNGGM PAIAQGAMTG GLVYLIVALI VKFAGKGWID 
121:	KVLPPIVVGP IVMVIGLSLA PTAINDAMYT DVANLKGYSL AYIIIALITV LSIVIYSIYG 
181:	KGFLSVVPIL LGIITGYVAA MIIGKITGMN IVSFTGISHA KWLTIPPMEI PFANYKWAFY 
241:	PSAILTMAPI AFVTMTEHFG HIMVLNSLTK KDYFKEPGLE KTLTGDGLAQ IIAGFIGAPP 
301:	VTSYGENIGV MAITKIHSIY VIAGAAVLAI VVSFIGKITA LLQSIPAPVI GGASIALFGV 
361:	IAASGLKILV ENKVNFDIKR NLLISSVVLV IGIGGMIINI TQNLQISSVA IATILGIVLN 
421:	LVLPKDPSEI