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2.A.40.1.4
Uracil permease

Accession Number:P39766
Protein Name:Uracil permease
Length:435
Molecular Weight:45452.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Uracil

Cross database links:

eggNOG: COG2233
HEGENOM: HOG000038200
Entrez Gene ID: 936604   
Pfam: PF00860   
KEGG: bsu:BSU15480   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (4)

[1] “Functional organization and nucleotide sequence of the Bacillus subtilis pyrimidine biosynthetic operon.”  Quinn C.L.et.al.   1709162
[2] “Regulation of the Bacillus subtilis pyrimidine biosynthetic (pyr) gene cluster by an autogenous transcriptional attenuation mechanism.”  Turner R.J.et.al.   8206849
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSKKKVNLGV RDVPTPFSWV SFSLQHLFAM FGSTILVPKL VGMSPAVALV TSGIGTLAYL 
61:	LITKGQIPAY LGSSFAFISP IILVKATGGP GAAMVGAFLA GLVYGLIALL IRQLGTGWLM 
121:	KILPPVVVGP VIIVIGLGLA STAVNMAMYA DPNASELVYS LKHFSVAGVT LAITIICAIF 
181:	LRGFLSLIPV LIGIIGGYLF ALTQGIVNFQ PVLDAKWFAV PEFIIPFKDY SPSVTLGIAA 
241:	AMVPVAFVTM SEHIGHQMVL SKVVGQDFIK KPGLHRSIMG DSVATILASL IGGPPTTTYG 
301:	ENIGVLAITR VFSVFVIGGA AVIALCFGFI GKISALISSV PSAVMGGVSF LLFGIIASSG 
361:	LRMLIDNKID YENNRNLIIT SVILVIGVGG AFIQVSQGGF QVSGMALAAI VGVILNLILP 
421:	QAKEEQADTS EQHHI