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2.A.40.6.3
High affinity (Km = 30 ┬ÁM) uric acid-xanthine transporter; leaf permease protein 1, LPE1 (necessary for proper chloroplast development in maize) (Argyrou et al., 2001)

Accession Number:Q41760
Protein Name:LPE1
Length:527
Molecular Weight:58122.00
Species:Zea mays (Maize) [4577]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Uric acid-xanthine

Cross database links:

RefSeq: NP_001105384.1   
Entrez Gene ID: 542332   
Pfam: PF00860   
BioCyc: MetaCyc:MONOMER-14782   
KEGG: zma:542332   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (2)

[1] “Leaf permease1 gene of maize is required for chloroplast development.”  Schultes N.P.et.al.   8721750
[2] “Functional characterization of a maize purine transporter by expression in Aspergillus nidulans.”  Argyrou E.et.al.   11283348

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MPPVKAEDLV VHAVKEQFAG LDYCITSPPP WITTVLVGFQ HYLVMLGTTV LIATIIVPLM 
61:	GGGHAEKAIV IQTILFLSGI NTLLQVHFGT RLPAVMSGSY TYIYPAVAII LSPRYALLID 
121:	PLERFVFTMR SLQGALIIAG VFQAVVGFFG IWRVFIRFLS PLAAVPFVTL TGLGLFFFAF 
181:	PGVTKCIEVG LPALVLLVIF AEYASHLFAK GSFVFSRCAV LVTVVIIWIY AEILTAAGAY 
241:	NERGPVTQFS CRADRSGIIQ GSPWVRFPYP FQWGYPIFCF QDCFAMLAAS FASLIESTGT 
301:	LIAVSRYSGA TFCPPSVFSR GIGWEGISII LDGMCGTLTG TAASVENAGL LAVTRVGSRR 
361:	VIKISALFMI FFSLFAKFGA VLASIPLPIF AALYCVLFAY SAGAGFSLLQ YCNLNSLRTK 
421:	FILSISLFLG LSIPQYFRVY EMFFGFGPVH THSVAFNVMV NVIFSSPATV AAILAYLLDC 
481:	THLYWEASVK KDRGWFWWEK FKSYKYDGRS EEFYRLPYGL SRYFPSL