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2.A.40.6.4
solute carrier family 23 (nucleobase transporters), member 3, SVCT3 or SLC23A3.  Function not certain as of 1/2013 (Bürzle et al. 2013).

Accession Number:Q6PIS1
Protein Name:Solute carrier family 23 member 3
Length:610
Molecular Weight:64531.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Nucleobases

Cross database links:

Genevestigator: Q6PIS1 Q6PIS1
eggNOG: NOG295794 NOG295794
HEGENOM: HOG000082411 HOG000082411
Entrez Gene ID: 151295   
Pfam: PF00860   
KEGG: hsa:151295    hsa:151295   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (6)

[1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[2] “Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”  Hillier L.W.et.al.   15815621
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[5] “Generation and annotation of the DNA sequences of human chromosomes 2 and 4.”  Hillier L.W.et.al.   15815621
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSRSPLNPSQ LRSVGSQDAL APLPPPAPQN PSTHSWDPLC GSLPWGLSCL LALQHVLVMA 
61:	SLLCVSHLLL LCSLSPGGLS YSPSQLLASS FFSCGMSTIL QTWMGSRLPL VQAPSLEFLI 
121:	PALVLTSQKL PRAIQTPGNS SLMLHLCRGP SCHGLGHWNT SLQEVSGAVV VSGLLQGMMG 
181:	LLGSPGHVFP HCGPLVLAPS LVVAGLSAHR EVAQFCFTHW GLALLVILLM VVCSQHLGSC 
241:	QFHVCPWRRA STSSTHTPLP VFRLLSVLIP VACVWIVSAF VGFSVIPQEL SAPTKAPWIW 
301:	LPHPGEWNWP LLTPRALAAG ISMALAASTS SLGCYALCGR LLHLPPPPPH ACSRGLSLEG 
361:	LGSVLAGLLG SPMGTASSFP NVGKVGLIQA GSQQVAHLVG LLCVGLGLSP RLAQLLTTIP 
421:	LPVVGGVLGV TQAVVLSAGF SSFYLADIDS GRNIFIVGFS IFMALLLPRW FREAPVLFST 
481:	GWSPLDVLLH SLLTQPIFLA GLSGFLLENT IPGTQLERGL GQGLPSPFTA QEARMPQKPR 
541:	EKAAQVYRLP FPIQNLCPCI PQPLHCLCPL PEDPGDEEGG SSEPEEMADL LPGSGEPCPE 
601:	SSREGFRSQK