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2.A.40.6.6
Nucleobase-ascorbate transporter 12 (AtNAT12)

Accession Number:Q3E7D0
Protein Name:Nucleobase-ascorbate transporter 12
Length:709
Molecular Weight:76674.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Nucleobase-ascorbate

Cross database links:

Genevestigator: Q3E7D0
eggNOG: COG2233
HEGENOM: HOG000038202
Entrez Gene ID: 817328   
Pfam: PF00860   
KEGG: ath:AT2G27810   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (4)

[1] “Identification and expression analysis of twelve members of the nucleobase-ascorbate transporter (NAT) gene family in Arabidopsis thaliana.”  Maurino V.G.et.al.   16982705
[2] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.”  Lin X.et.al.   10617197
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry.”  Nuehse T.S.et.al.   14506206

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSSSDPKPGP KPGPWPPTPE SAAMPPSSWA KKTGFRPKFS GETTATDSSS GQLSLPVRAK 
61:	QQETQPDLEA GQTRLRPPPP VSAAVTNGET DKDKKEKPPP PPPGSVAVPV KDQPVKRRRD 
121:	SDGVVGRSNG PDGANGSGDP VRRPGRIEET VEVLPQSMDD DLVARNLHMK YGLRDTPGLV 
181:	PIGFYGLQHY LSMLGSLILV PLVIVPAMGG SHEEVANVVS TVLFVSGITT LLHTSFGSRL 
241:	PLIQGPSFVF LAPALAIINS PEFQGLNGNN NFKHIMRELQ GAIIIGSAFQ AVLGYSGLMS 
301:	LILRLVNPVV VAPTVAAVGL SFYSYGFPLV GKCLEIGVVQ ILLVIIFALY LRKISVLSHR 
361:	IFLIYAVPLS LAITWAAAFL LTETGAYTYK GCDPNVPVSN VVSTHCRKYM TRMKYCRVDT 
421:	SHALSSAPWF RFPYPLQWGV PLFNWKMAFV MCVVSVIASV DSVGSYHASS LLVASRPPTR 
481:	GVVSRAIGLE GFTSVLAGLW GTGTGSTTLT ENVHTIAVTK MGSRRVVELG ACVLVIFSLV 
541:	GKVGGFLASI PQVMVASLLC FMWAMFTALG LSNLRYSEAG SSRNIIIVGL SLFFSLSVPA 
601:	YFQQYGISPN SNLSVPSYYQ PYIVSSHGPF KSQYKGMNYV MNTLLSMSMV IAFIMAVILD 
661:	NTVPGSKQER GVYVWSDSET ATREPALAKD YELPFRVGRF FRWVKWVGI