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2.A.40.7.1
The purine (hypoxanthine/adenine/guanine) transporter, AzgA (Cecchetto et al., 2004).  Topological modeling has revealed a potential substrate binding cavity, and residues important for transport activity have been identified (Krypotou et al. 2014).

Accession Number:Q7Z8R3
Protein Name:AzgA
Length:580
Molecular Weight:62089.00
Species:Emericella nidulans (Aspergillus nidulans) [162425]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate Hypoxanthine, Adenine, guanine

Cross database links:

RefSeq: XP_681803.1   
Entrez Gene ID: 2868800   
Pfam: PF00860   
KEGG: ani:AN8534.2   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0055085 P:transmembrane transport

References (2)

[1] “The AzgA Purine Transporter of Aspergillus nidulans (subtitle: characterization of a protein belonging to a new phylogenetic cluster).”  Cecchetto G.et.al.   14597637
[2] “Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.”  Galagan J.E.et.al.   16372000

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MGYAEWIGRT NAAVARSPVG RWFRLEGSGH PRERKGAYFF TELRAGLATF FAMAYIISVN 
61:	ANITSDTGGT CVCPAEDLAT ACDNNTEYLL CKQEVNRDLV TATAAIAAIA SFFLGLLANL 
121:	PVALAPGMGL NAYFAYTVVG HHGTGLIPYS LAVTAVFVEG WIFLGLTLLG IRQWLARAIP 
181:	ASIKLATGAG IGLYLTLIGL SYSAGLGVVQ GGTSSPIQLA GCASDTFGDD GLCPSSEKMR 
241:	NPTMWIGIFC GGVFTVFLMM YRVKGAVIAG ILLVSIISWP RPTPVTYFPH TETGDSSFDF 
301:	FKKVVTFHPI QHTLVAQEWN ISSNGGQFGL ALITFLYVDI LDATGTLYSM AKFAGAMDER 
361:	TQDFEGSAMA YMVDAICISI GSLFGSPPVT AFVESGAGIS EGGKTGLTSC MTGICFFIAV 
421:	FFAPIFASIP PWATGSTLVI VGSMMMHATL EINWRYLGDA VPAFLTISLM PFTYSIADGL 
481:	IAGILSYILI NGGVWIVAKL TGGRISPPNR EEEHEPWTWK IPGGFFPPWL VRAVHGKKDF 
541:	WRAEDDANDL SLGVMPHGSL SSQDRAGEKL ASSKEQVTEK