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2.A.40.7.3
The purine transporter Azg1 (takes up 8-azadenine and 8-azaguanine but not other toxic nucleobase analogues; similar to Azg2 of A. thaliana (Q84MA8); (Mansfield et al. 2009).

Accession Number:Q9SRK7
Protein Name:At3g10960
Length:579
Molecular Weight:61669.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Purines, 8-azadenine

Cross database links:

Genevestigator: Q9SRK7
RefSeq: NP_566384.1   
Entrez Gene ID: 820267   
Pfam: PF00860   
KEGG: ath:AT3G10960   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005345 F:purine transmembrane transporter activity
GO:0015853 P:adenine transport
GO:0015854 P:guanine transport
GO:0055085 P:transmembrane transport

References (3)

[1] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis.”  Mansfield T.A.et.al.   19121308

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEQQQQQQLP STTTRPKPKL LNRLNTYVGS SRVGKRFKLA ERNSTFTTEL RAGTATFLTM 
61:	AYILAVNASI LSDSGGTCSV SDCIPLCSNP AIEPSQCTGP GLRLIQPDVS CKFNPVNPGY 
121:	AACVEEIRKD LIVATVAASL IGCVIMGLMA NLPLALAPGM GTNAYFAYTV VGFHGSGSIS 
181:	YRTALAAVFI EGLIFLFISA IGFRAKLAKL VPKPVRISSS AGIGLFLAFI GLQNNQGIGL 
241:	VGYSPSTLVT LAACPASSRI SLAPVITSAN GTVSLLAGGS VSGDIMCIHG RMESPTFWLG 
301:	IVGFVIIAYC LVKNVKGAMI YGIVFVTAVS WFRNTEVTAF PNTSAGDAAH DYFKKIVDVH 
361:	VIKHTAGALS FSGINKGHFW EALVTFLYVD ILDTTGTLYS MARFAGFVDE KGDFAGQYFA 
421:	FMSDASAIVI GSLLGTSPVT VFIESSTGIR EGGRTGLTAI TVAVYFLLAM FFTPLLASIP 
481:	AWAVGPPLIL VGVMMMKSVT EIDWEDMREA IPAFVTMILM PLTYSVAYGL IGGIGSYVVL 
541:	HLWDWGEEGL VKLGFLKRKV KEEDNNNGVV KASEIDTTV