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2.A.40.7.7
Guanine/hypoxanthine uptake porter of 455 aas, YgfQ.  Also takes up mutagens such as 1-methylguanine, 8-azaguanine, 6-thioguanine, and 6-mercaptopurine (Papakostas et al. 2013).

Accession Number:Q46817
Protein Name:Putative permease YgfQ
Length:455
Molecular Weight:46758.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Hypoxanthine, guanine

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
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  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSGDILQTPD APKPQGALDN YFKITARGST VRQEVLAGLT TFLAMVYSVI VVPGMLGKAG 
61:	FPPAAVFVAT CLVAGFGSLL MGLWANLPMA IGCAISLTAF TAFSLVLGQQ ISVPVALGAV 
121:	FLMGVIFTAI SVTGVRTWIL RNLPMGIAHG TGIGIGLFLL LIAANGVGMV IKNPIEGLPV 
181:	ALGAFTSFPV MMSLLGLAVI FGLEKCRVPG GILLVIIAIS IIGLIFDPAV KYHGLVAMPS 
241:	LTGEDGKSLI FSLDIMGALQ PTVLPSVLAL VMTAVFDATG TIRAVAGQAN LLDKDNQIIN 
301:	GGKALTSDSV SSIFSGLVGA APAAVYIESA AGTAAGGKTG LTATVVGALF LLILFLSPLS 
361:	FLIPGYATAP ALMYVGLLML SNVSKLDFND FIDAMAGLVC AVFIVLTCNI VTGIMLGFVT 
421:	LVVGRVFARE WQKLNIGTVI ITAALVAFYA GGWAI