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2.A.41.1.2
Pyrimidine-specific nucleoside:H+ symporter, NupC

Accession Number:P39141
Protein Name:NupC
Length:393
Molecular Weight:42496.00
Species:Bacillus subtilis [1423]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Pyrimidine, H+

Cross database links:

HEGENOM: HBG713614
RefSeq: NP_391820.2   
Entrez Gene ID: 937534   
Pfam: PF07662    PF01773   
KEGG: bsu:BSU39410   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005415 F:nucleoside:sodium symporter activity
GO:0006810 P:transport

References (4)

[1] “Dra-nupC-pdp operon of Bacillus subtilis: nucleotide sequence, induction by deoxyribonucleosides, and transcriptional regulation by the deoR-encoded DeoR repressor protein.”  Saxild H.H.et.al.   8550462
[2] “Cloning and sequencing of a 23-kb region of the Bacillus subtilis genome between the iol and hut operons.”  Yoshida K.et.al.   8867804
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKYLIGIIGL IVFLGLAWIA SSGKKRIKIR PIVVMLILQF ILGYILLNTG IGNFLVGGFA 
61:	KGFGYLLEYA AEGINFVFGG LVNADQTTFF MNVLLPIVFI SALIGILQKW KVLPFIIRYI 
121:	GLALSKVNGM GRLESYNAVA SAILGQSEVF ISLKKELGLL NQQRLYTLCA SAMSTVSMSI 
181:	VGAYMTMLKP EYVVTALVLN LFGGFIIASI INPYEVAKEE DMLRVEEEEK QSFFEVLGEY 
241:	ILDGFKVAVV VAAMLIGFVA IIALINGIFN AVFGISFQGI LGYVFAPFAF LVGIPWNEAV 
301:	NAGSIMATKM VSNEFVAMTS LTQNGFHFSG RTTAIVSVFL VSFANFSSIG IIAGAVKGLN 
361:	EKQGNVVARF GLKLLYGATL VSFLSAAIVG LIY