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2.A.41.1.3
The purine nucleoside uptake transporter NupG (YxjA) (Johansen et al., 2003)

Accession Number:P42312
Protein Name:NupG aka YxjA
Length:397
Molecular Weight:43719.00
Species:Bacillus subtilis [1423]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Purines

Cross database links:

HEGENOM: HBG713614
RefSeq: NP_391781.2   
Entrez Gene ID: 937472   
Pfam: PF07662    PF01773   
KEGG: bsu:BSU39020   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005415 F:nucleoside:sodium symporter activity
GO:0006810 P:transport

References (4)

[1] “Sequencing of a 65 kb region of the Bacillus subtilis genome containing the lic and cel loci, and creation of a 177 kb contig covering the gnt-sacXY region.”  Yoshida K.et.al.   8969509
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.”  Barbe V.et.al.   19383706
[4] “Definition of a second Bacillus subtilis pur regulon comprising the pur and xpt-pbuX operons plus pbuG, nupG (yxjA), and pbuE (ydhL).”  Johansen L.E.et.al.   12923093

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYFLLNLVGL IVIMAVVFLC SPQKKKIKWR PIITLIVLEL LITWFMLGTK VGSWAIGKIG 
61:	DFFTWLIACA SDGIAFAFPS VMANETVDFF FSALLPIIFI VTFFDILTYF GILPWLIDKI 
121:	GWVISKASRL PKLESFFSIQ MMFLGNTEAL AVIRQQLTVL SNNRLLTFGL MSMSSISGSI 
181:	IGSYLSMVPA TYVFTAIPLN CLNALIIANL LNPVHVPEDE DIIYTPPKEE KKDFFSTISN 
241:	SMLVGMNMVI VILAMVIGYV ALTSAVNGIL GVFVHGLTIQ TIFAYLFSPF AFLLGLPVHD 
301:	AMYVAQLMGM KLATNEFVAM LDLKNNLKSL PPHTVAVATT FLTSFANFST VGMIYGTYNS 
361:	ILDGEKSTVI GRNVWKLLVS GIAVSLLSAA IVGLFVW