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2.A.43.1.2
Cystinosin homolog

Accession Number:Q9VCR7
Protein Name:Cystinosin homolog
Length:397
Molecular Weight:44588.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Lysosome membrane1 / Multi-pass membrane protein2
Substrate Cystine, H+

Cross database links:

eggNOG: NOG266153
Entrez Gene ID: 42723   
KEGG: dme:Dmel_CG1711   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005765 C:lysosomal membrane
GO:0015171 F:amino acid transmembrane transporter activity

References (4)

[1] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132
[2] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572
[3] “A Drosophila full-length cDNA resource.”  Stapleton M.et.al.   12537569
[4] “Identification of N-glycosylated proteins from the central nervous system of Drosophila melanogaster.”  Koles K.et.al.   17893096

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MDFSTHRLTT LLLLLLATVA LGNAQSSQLT VDSHDITVLL NSNETFLVFA NGLLDSDVEV 
61:	ALGTDSEDHL LLDPATFVYP AGSTRNQSVV ITGLKAGNVK VVADSDDANK EIVKDVFVRV 
121:	TVAKSRALIY TSIIFGWVYF VAWSVSFYPQ IWSNYRRKSV EGLNFDFLAL NIVGFTLYSM 
181:	FNCGLYFIED LQNEYEVRYP LGVNPVMLND VVFSLHAMFA TCITILQCFF YQRAQQRVSF 
241:	IAYGILAIFA VVVVVSAGLA GGSVIHWLDF LYYCSYVKLT ITIIKYVPQA LMNYRRKSTS 
301:	GWSIGNILLD FTGGTLSMLQ MILNAHNYDD WVSIFGDPTK FGLGLFSVLF DVFFMLQHYV 
361:	FYRHSRESSS SDLTTVTDVQ NRTNESPPPS EVTTEKY