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2.A.47.1.13
The Na+-coupled dicarboxylate (succinate; malate; fumarate) transporter, SdcL (transports aspartate, α-ketoglutarate and oxaloacetate with low affinity). Km for succinate, ~6 μM; Km for Na+, 0.9 mM; Na :substrate = 2:1 (Strickler et al., 2009).

Accession Number:Q65NC0
Protein Name:Putative uncharacterized protein
Length:546
Molecular Weight:59161.00
Species:Bacillus licheniformis (strain DSM 13 / ATCC 14580) [279010]
Number of TMSs:14
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Na+, Dicarboxylates, Succinate, malate, Fumarate, Alpha-ketoglutarate, Oxaloacetate

Cross database links:

eggNOG: COG0471
HEGENOM: HBG616159
RefSeq: YP_077725.1    YP_090137.1   
Entrez Gene ID: 3030087    3101037   
Pfam: PF00939   
BioCyc: BLIC279010-1:BLI00488-MONOMER    BLIC279010:BL01772-MONOMER   
KEGG: bld:BLi00488    bli:BL01772   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (2)

[1] “The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential.”  Veith B.et.al.   15383718
[2] “Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species.”  Rey M.W.et.al.   15461803

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKSSVVSAWD MLWRSHREAK RLLLFAMPVR AGKDAGLKIN SEQTMKEEKP PSYKTPQKIG 
61:	LLLGPALFFA VLLFFFPEGL SYEGRMVLAT TLWVAVWWIT EAVPIPAASL LPIVLLPLTG 
121:	ALEGAAVTSS YGDPIVFLFL GGFLIALAME RWNLHKRIAL NIISVVGTST SRIVLGFMAA 
181:	TGFLSMWVSN TAAVMMMLPI GTAIIHQVSA VIKSERKDLA AEEAKFSKAL IFSIGYAGTI 
241:	GGLGTLIGTP PNIILAANIK KLYGVEVSFG GWMAFAVPVV VILLVAVWLY LTKVAHPIKM 
301:	KELPGGKELI LEEKRKLGKM SFEETMVLLV FGFAAFMWVT RTFLWDDKIP GIDDTMIAIF 
361:	AASLLFLIPS LNKGGRVLDW SVSKDLPWGI LLLFGGGLAL ATGFKETGLA EWIGGRLTVL 
421:	DGFNFVVIVI ISTALVLFLT EITSNTATAT MILPVLASLA LALNVHPYAL MVPAAMAANC 
481:	AFMLPVGTPP NAIIFASGKL KISEMVRTGF VINIFTLILI VGAVFYILPH LWGVDLTVFP 
541:	DNLKSN