TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.47.1.5
Basolateral Na+: di- and tricarboxylate (succinate cis-aconitate, citrate, etc.) cotransporter, fNaDC-3

Accession Number:Q9W7I2
Protein Name:fNaDC-3 aka NADC3
Length:601
Molecular Weight:66408.00
Species:Pseudopleuronecta americanus (Winter flounder) [8265]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Na+, Tricarboxylates, Dicarboxylates

Cross database links:

Pfam: PF00939   

Gene Ontology

GO:0016020 C:membrane
GO:0005215 F:transporter activity
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Expression cloning and characterization of a novel sodium-dicarboxylate cotransporter from winter flounder kidney.”  Steffgen J.et.al.   10400635

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKISVVSKKL WCVHKQLILL IAPLIFLPLI FTLPEKEGRC LYVVLLMATF WCTEALPLAV 
61:	TAMLPVCLFP TLGIIPSKQI CPQYFLETNF LFLSGLVMAS SIEEWGLHRR IALKVLSIVG 
121:	VKPAWLIFGM MMTSAFLSMW LSNTATTAMM LPIANAILES LFGDLETLKK NCKSPKDSDS 
181:	DIINGQCTLK MHSLPAVPVE KQLLSIEGTD GPEPADVRTA EEIRSESEYQ LKVWKGFLIC 
241:	IPYAASIGGT ATLTGTAPNL ILIGQLKSYF PDCDLINFGS WFAFAFPLML IFLFVGWLWI 
301:	AYLYGGLNTR LCIQRHDRRA QAEARAQALI QDDYRKLGPM NFAQGAIAFF FVLFAVLLFT 
361:	RDPKFITGWS VFFKKGYVSD AVTGVIIVSI LFFFPSQKPS LNWWFDPQAS NTRYVPLLSW 
421:	QKAQDSIPWN IILLLGGGFA MAKACEESGL ASWIGGHLQP LAEVPPAAAV MLITAFLACF 
481:	TEFASNTATI IIFLPVIAEL AIRVSVHPLY FMIPATVGCS YAFMLPVSTP PNSIAFASGH 
541:	LMVKDMVKTG FVMNILGILC VSLAMNTWGV AMFDLHTYPD WAHPINKTAA AEVVQALNAT 
601:	L