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2.A.47.1.6
The tonoplast dicarboxylate (malate) transporter, AtDCT (Kovermann et al., 2007).  The ortholog (70% identity) in tomatos increases the malate while decreasing the citrate concentrations, influencing flavor (Liu et al. 2017).

Accession Number:Q8LG88
Protein Name:Tonoplast dicarboxylate transporter
Length:540
Molecular Weight:58098.00
Species: [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate Citrate, malate

Cross database links:

Genevestigator: Q8LG88
HEGENOM: HBG616159
RefSeq: NP_199567.1   
Entrez Gene ID: 834806   
Pfam: PF00939   
KEGG: ath:AT5G47560   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005774 C:vacuolar membrane
GO:0015140 F:malate transmembrane transporter activity
GO:0015743 P:malate transport
GO:0051453 P:regulation of intracellular pH
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (3)

[1] “The plant homolog to the human sodium/dicarboxylic cotransporter is the vacuolar malate carrier.”  Emmerlich V.et.al.   12947042
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “Impaired pH homeostasis in Arabidopsis lacking the vacuolar dicarboxylate transporter and analysis of carboxylic acid transport across the tonoplast.”  Hurth M.A.et.al.   15728336

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNGGDVTVAG SDDLKSPLLP VVHNDEPFER QTVGQQLRTI FTPKNCYIAL GPLLCAVVCL 
61:	CVDLGGDETT TARNMLGVLV WMFAWWLTEA VPMPITSMTP LFLFPLFGIS AADDVANSYM 
121:	DDVISLVLGS FILALAVEHY NIHRRLALNI TLVFCVEPLN APLLLLGICA TTAFVSMWMH 
181:	NVAAAVMMMP VATGILQRLP SSSSTTEVVH PAVGKFSRAV VLGVIYSAAV GGMSTLTGTG 
241:	VNLILVGMWK SYFPEADPIS FSQWFFFGFP LALCIFVVLW CVLCVMYCPK GAGQALSPYL 
301:	HKSHLRRELD LLGPMNFAEK MVLAVFGGLV VLWMTRNITD DIPGWGRIFA GRAGDGTVSV 
361:	MMATLLFIIP SNIKKGEKLM DWNKCKKLPW NIVLLLGAGF AIADGVRTSG LAEVLSKGLV 
421:	FLETAPYWAI APTVCLIAAT ITEFTSNNAT TTLLVPLLIE IAKNMGIHPL LLMVPGAIGA 
481:	QFAFLLPTGT PSNVVGFTTG HIEIKDMIKT GLPLKIAGTI FLSILMPTLG AYVFASMGGV