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2.A.47.2.3
Low affinity phosphate transporters (881aas). Also transports selenite (Lazard et al., 2010).  

Accession Number:P39535
Protein Name:Low-affinity phosphate transporter PHO90
Length:881
Molecular Weight:97689.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate phosphate, Selenite

Cross database links:

Genevestigator: P39535
eggNOG: fuNOG07970
HEGENOM: HBG329859
Entrez Gene ID: 853241   
Pfam: PF00939    PF03105   
KEGG: sce:YJL198W   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015114 F:phosphate transmembrane transporter activity
GO:0006814 P:sodium ion transport

References (6)

[1] “The sequence of a 36 kb segment on the left arm of yeast chromosome X identifies 24 open reading frames including NUC1, PRP21 (SPP91), CDC6, CRY2, the gene for S24, a homologue to the aconitase gene ACO1 and two homologues to chromosome III genes.”  Purnelle B.et.al.   7754713
[2] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.”  Galibert F.et.al.   8641269
[3] “Phosphate transport and sensing in Saccharomyces cerevisiae.”  Wykoff D.D.et.al.   11779791
[4] “Transcriptional regulation of phosphate-responsive genes in low-affinity phosphate-transporter-defective mutants in Saccharomyces cerevisiae.”  Auesukaree C.et.al.   12821119
[5] “Global analysis of protein expression in yeast.”  Ghaemmaghami S.et.al.   14562106
[6] “Transport and signaling through the phosphate-binding site of the yeast Pho84 phosphate transceptor.”  Popova Y.et.al.   20133652

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRFSHFLKYN AVPEWQNHYM DYSELKNLIY TLQTDELQVG DNEEGFGAGK SSNITDRFKN 
61:	KFSFKNAKED TSSGMNKDAG IVEETIELRE LPTAQTVAAK PSPFRRMKEK IFYKRRSSSA 
121:	SSVSSTANEN LQLDTYDTFV GDLTAEKQKV DDFYKRTEAK FYDKFDALVK DLKKIGVIEY 
181:	DIDDDTLFNE PIASTNDEVP PLDLDDDEDD DEFYDDQSNI EDNTALLHHS QYNIKSQKKS 
241:	LLKKSIVNLY IDLCQLKSFI ELNRIGFAKI TKKSDKVLHL NTRTELIESE QFFKDTYAFQ 
301:	AETIELLNSK ISQLVTFYAR ITDRPHNISH SKQELKSYLH DHIVWERSNT WKDMLGLLSQ 
361:	ADELTPKETE YNANKLVGKL DLEYYRWPLP RPINLKFTSI NNVALPKLFF TKKAYKIYFI 
421:	ILVTGLLLGI KTFNDAAQHR CMALVECVAF LWASEAIPLH ITAFLVPLLV VLFKVLKTSD 
481:	GAIMSAASAS SEILAAMWSS TIMILLAGFT LGEVLAQYNI AKVLASWLLA FAGCKPRNVL 
541:	LMAMCVVFFL SMWISNVAAP VLTYSLLSPL LDAMDADSPF AQALVLGVAL AANIGGMSSP 
601:	ISSPQNIISM SYLKPYGIGW GQFFAVALPS GILAMLLVWI LLFTTFKMNK TKLEKFKPIK 
661:	TKFTVKQYYI ITVTVATILL WCVESQIEGA FGSSGQIAII PIVLFFGTGL LSTQDLNAFP 
721:	WSIVILAMGG IALGKAVSSS GLLSTIAKAL QKKIENDGVF AILCIFGILM LVVGTFVSHT 
781:	VSAIIIIPLV QEVGDKLGNP KAAPILVFGC ALLSSCGMGL ASSGFPNVTA ISKVDRKGDR 
841:	YLSVMTFLTR GVPASILAFL CVITLGYGIM ASVVKGNATS A