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2.A.47.2.4
Contractile vacuole phosphate:Na+ symporter of 727 aas and 12 TMSs, Pho91 (Pho90; Pho87).  Has an N-terminal SPX domain and a C-terminal anion permease domain. Plays an indirect role in pyrophosphate and oligophosphate synthesis (Jimenez and Docampo 2015).  Pyrophosphate stimulates the phosphate-sodium symporter of Trypanosoma brucei acidocalcisomes and Saccharomyces cerevisiae vacuoles (Potapenko et al. 2019).

Accession Number:Q4DX24
Protein Name:Sodium/sulphate symporter, putative
Length:727
Molecular Weight:80492.00
Species:Trypanosoma cruzi (strain CL Brener) [353153]
Number of TMSs:12
Substrate phosphate, Na+

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKFGKRFQEE MVEQWRESYV NYKALKQLIY HSELSGVEFS RDFFAMVTEE LEKAEGLFQD 
61:	LLDELQQSHD ELLEQDPDLP VMNPIRTLRF YRKRVHRDTR STNGSGDSEV FDSSRASSTV 
121:	DPEPGRRGCI PSVVKSLFLL IIGDSHKRAF DEHAPRAKFA EWHSSAHKLQ HFAELNLEAV 
181:	RKAAKKLKKH RRREGDFTIA IEAEINRSRL VTLMPRLRSL MADIDSDYER KFGDSLDQYK 
241:	NVAMQQAYHA KWQFVFLSAA LFCLLMFLPI LSEHPPAHNC VALFGLIVSL WITEAIPFFC 
301:	TAMLIPIVAV PLGIIADPHT NEVANSTVAS GIILGKVMDH VQILVLGGLT IGKALARTNL 
361:	EAYAATALYR LTAHRPPFYL LGVMLWSGVL CAFVSNVAAP LLVLGVIQRT LWEFPEDTEA 
421:	PHGILLGLAF ACNIGGMLSP IASPQNAVAM NVLRFHSVSF AAWIAVALPI VLFSIVAAWA 
481:	IILVVWKPFK DVKGIPLHVV STESGKDTRV TDRVVVVVVS LITIILWIIS PDVLFGDTGV 
541:	VALIPIVVFF GTGILAKEDF NTLSWHLMFL LAGGNMLGLC AHDSKMLDIL AHSMHGTLVS 
601:	QPPYLTFVLV ILVVALATTF VSHTVSAMIL LPIIAKIGFL LPKHEGILSV TPATLVMLSA 
661:	LMCSGAMAFP ISSFPNVNSL LAEDSTGQPY LKAKDFLFCG TLITLLFLFC LVTWMIPLAY 
721:	VVLEGFN