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2.A.47.4.2
Antimonite resistance protein (inducible by both arsenite and antimonite).

Accession Number:Q9HMC9
Protein Name:ArsB
Length:618
Molecular Weight:65011.00
Species:Halobacterium sp. [2242]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Mitochondrion inner membrane1 / Multi-pass membrane protein2
Substrate antimonite

Cross database links:

HEGENOM: HBG349422
RefSeq: NP_281162.1   
Entrez Gene ID: 1448949   
Pfam: PF03600    PF00939    PF02080   
BioCyc: HSP64091:VNG2602G-MONOMER   
KEGG: hal:VNG2602G   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005488 F:binding
GO:0003824 F:catalytic activity
GO:0008324 F:cation transmembrane transporter activity
GO:0015137 F:citrate transmembrane transporter activity
GO:0015746 P:citrate transport
GO:0008152 P:metabolic process
GO:0006813 P:potassium ion transport
GO:0006814 P:sodium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Genome sequence of Halobacterium species NRC-1.”  Ng W.V.et.al.   11016950

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MSAVSPPVAL AAGVSTDVLV VFGVVVGALV LFVTEWLPID VTAILIMVVL AVLEPWTQVS 
61:	TAESLSGFSN KATIAVLAML ILSTGVSRTG LVQLVGRKLS AFAGENKSRQ LGATIAAGGP 
121:	VSGFVNNTPV VAILVPVISD LAHKGKTSPS KLLMPLSFAS MLGGTLTLIG TSTNLLASET 
181:	TARLADQQGI AGLHAFSMFE FTHLGVLVLA VGSLYLFVVA PRLLSDRVPV EDDYLTEYAL 
241:	GDYLSEVVVR ESSPIVGQTV RAAIDADRFD ADVLGLVRDG ERFIEPLGQK VVRAGDTLTI 
301:	RTGRETLADI ATVDDLSLTG APDDERDLEP TTQDEQALVE VVIHSGSSLA GQTLSSSSFR 
361:	DRYDANVLAF RSRGETVHER MDDRRLRVGD TLLVQAPRSG IDRLSANPDF IVAHEPDEPD 
421:	YRTEKIPHAI GIVLGVVLAA TVTPFHIVTT ALGGVVAMVS TGVLHPSEVY DSVDWDVIFL 
481:	LAGVIPLGIA LEQTGAAQLL GEAMAATATV LPALGVLWVF YLFTGVITSV ISNNASVVLL 
541:	IPVAVEAAVE LGANPFAFVL AVTFAASTAF MTPVGYQTNL FVYGPGGYTF SDFFRVGLPL 
601:	QLLLSVVTVG GIAAFWGV