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2.A.48.1.6
Giardia RFC homologue

Accession Number:A8BIM9
Protein Name:RFC homologue
Length:499
Molecular Weight:54874.00
Species:Giardia lamblia ATCC 50803 [184922]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate folate

Cross database links:

eggNOG: KOG3810
RefSeq: XP_001706868.1   
Entrez Gene ID: 5699763   
Pfam: PF01770   
KEGG: gla:GL50803_723   

Gene Ontology

GO:0016020 C:membrane
GO:0005542 F:folic acid binding
GO:0008518 F:reduced folate carrier activity
GO:0006810 P:transport

References (1)

[1] “Genomic minimalism in the early diverging intestinal parasite Giardia lamblia.”  Morrison H.G.et.al.   17901334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MAEIPEADVT NSTSNDYPHT DLKEESDKCN TRSDAPRAGS FNALLFLQVL LGILCAFKPA 
61:	EPFVVPYYID NGISMDQINQ TVFPMSGYSN FGFLLVLSMA SIGISHHALL YFGWVGYVVC 
121:	YTLLIFVDKL IVAIFAEVFY GLAVASETVY CATFYFLKNR TVSVMTSHLR ASTISRTTLL 
181:	VTHVISDLFG QLMVSFITNF SKRLLFIITA ISVSSSVVPL TILTCIQRHT PTSYFKVSKN 
241:	QVSDETSENG KNNDLCASSI GTEKMSRKLY LRGLSYVWGG GLAGVLPLYI GIFSLSGHTL 
301:	YQNYITNILY DVQQGTKDEL YGLFVMIGRL SGVLGSVLAL TCKKVKRTGI LQILLLFILS 
361:	CLLIIPAFVK HLIWLFVANV VEFAAAELTI TVMWAQLAAS CQLSVYPAVF LCQALIVAAI 
421:	VLIVQATVFN SVANEFEGFT ANQTHYLWCA VLGLTGLLIS LLVALVSRFR GSCRRGSKDN 
481:	ATKEDFDANP LLPDQSCEV