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2.A.49.1.2
The vascular wilt fungal CLC-type voltage-gated chloride channel, Clc1 (influences disease progression and stress responses) (Canero and Roncero, 2008).

Accession Number:A7LKG1
Protein Name:Clc1
Length:825
Molecular Weight:90989.00
Species:Fusarium oxysporum f. sp. lycopersici [59765]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Cl-

Cross database links:

Pfam: PF00571    PF00654   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0003824 F:catalytic activity
GO:0005247 F:voltage-gated chloride channel activity
GO:0006821 P:chloride transport
GO:0008152 P:metabolic process
GO:0055085 P:transmembrane transport

References (1)

[1] “Influence of the chloride channel of Fusarium oxysporum on extracellular laccase activity and virulence on tomato plants.”  Canero D.C.et.al.   18451056

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNVRQSSFSL APPGPGLERR PSVVSRLSSV FSNADQEAGS AARTGAGLIE EEIAEIKRYE 
61:	VDWVQDAARE QAKRKARRKQ AAGLYDKGQP GWRYQLWRSY DAAQAWIVVT IIGIAIGLNA 
121:	ALLNIITEWL SDVKMGYCET GFYLNENFCC WGEENGCDQW HRWTGFEPLN YFIYFTLFAC 
181:	VAGTLVKSFA PYAAGSGISE IKCIIAGFVM KGFLGWWTLI IKSVCLPLAI ASGLSVGKEG 
241:	PSVHYAVCTG NVISRLFDKY KRNASKTREF LSASAAAGVA VAFGSPIGGV LFSLEEMSNQ 
301:	FPLKTLWRSY FCALIATAVL AAMNPFRTGQ LVMFQVEYKN DWHFFELLFY VLIGIFGGLY 
361:	GAFVIKWNLR VQSFRKKYLK EYAVLEATLL AAGTAIIAYP NAFLRIDMTE SMEILFSECG 
421:	RGESYHGLCE PDKRWWNIIS LFLATFLRLF LVILSYGCKV PAGIFVPSMA IGASFGRTIG 
481:	ILVQAIHEAN PTSVFFSACK PDEPCITPGT YALLGAAAAL SGIMHITISV VVIMFELTGA 
541:	LNYILPTMIV VGVTKAVSEL FGKGGIADRM IWFSGMPFLD SKEEHNFGVP VSAVMRTSVV 
601:	SMPAHGLTLG EVQSLLADDR YQGFPVVEDK HTKVLVGYIG STELRYAIDK MSRTSPLSET 
661:	AKCTFAPSSA NLSSTSLNNI HGDSSHSSTL DFSRYVDATP VTAHPRLPLE TVMELFQKIG 
721:	PRVILIEYHG KLTGLVTVKD CLKYQFKVEA AENPKDDHRI EEGQEQLWAL FQRAGNWFSG 
781:	RVSRYSGGRI RLTSTSGGER PLGRGQILDG DEEVLDEGVE LESRR